Benign Prostat Hiperplazisi Tedavisinin Değerlendirmesinde Prostat Kapsüler Arter Rezistif İndeks Değerinin Etkinliği

Benign prostat hipertrofisi olan hastalarda prostat kapsüler arter rezistif indeksin hastalığın şiddetini belirleme ve uygulanan α-bloker tedavi etkinliğini değerlendirmede parametrik bir ölçüt olup olamayacağını değerlendirmeyi amaçladık. Hastanemize başvuran ve tedavi olan alt üriner sistem semptomları olan hastaların tedavi, işlem, tetkik aşamasında hasta bulguları ve görüntüleri kayıt altına alındı. Daha sonra retrospektif olarak bu kayıtlar ve hastanemiz verileri incelendi. Çalışmaya 66 hasta dahil edildi. IPSS skoru yüksek olup tedavi önerilen 36 hastanın rezistif indeks ortalama değeri 0,68±0,09 , IPSS skoru düşük olan hastaların rezistif indeks ortalama değeri 0,65±0,05 dır. Bu iki değer arasındaki fark istatiksel olarak anlamlı bulunmuştur(p<0,05). Alt üriner sistem semptomları olan ve tedavi verilen 36 tedavi öncesi rezistif indeks değeri ortalama 0,68±0,09 ’dir. Tedavi sonrasında ortalama 0,64±0,07 değere gerilemiştir. Bu gerileme istatistiksel olarak anlamlı bulunmuştur (p<0,05). Aynı şekilde tedavi öncesi ortalama 20,38±4,03 olan IPSS değeri tedavi sonrasında ortalama 14,38±3,69 ’e gerilemiş ve istatistiksel olarak anlamlı bulunmuştur (p<0,05). Prostat kapsüler arter rezistif indeks değeri benign prostat hipertrofisinin şiddetini saptama ve uygulanan alfa bloker tedavi etkinliğinin değerlendirilmesinde parametrik bir belirteç olduğunu düşünüyoruz.

Anahtar Kelimeler:

Benign prostat hiperplazisi, transrektal renkli doppler ultrason, uluslararası prostat semptom skoru, prostatik kapsüler arter rezistif indeksi

Effectiveness of Prostatic Capsular Artery Resistive İndex in the Evaluation of Benign Prostatic Hyperplasia Treatment

We aimed to evaluate whether the prostatic capsular artery resistive index can be a parametric criterion in evaluating the efficacy of α-blocker treatment and the severity of the disease in patients with benign prostatic hyperplasia. The clinical and diagnostic investigation findings and the radiographic images were recorded during the treatment and during the application of procedures in the patients who presented to our hospital with lower urinary system symptoms. Then, these data and the information of the respective patients recorded in the hospital database were examined retrospectively. A total of 66 patients were included in the study. Of the patients, 36 with higher IPSS were recommended to be treated and had a mean resistive index of 0.68±0.09, and the patients with lower IPSS had a mean resistive index of 0.65±0.05. The difference between these two values was found to be statistically significant (p<0.05). In 36 patients who were treated for lower urinary system symptoms, the mean resistive index before the treatment was 0.68±0.09. After the treatment, the mean resistive index decreased to 0.64±0.07. This decrease was statistically significant (p<0.05). The mean IPSS was 20.38±4.03 before the treatment and it decreased to 14.38±3.69 after the treatment, showing a statistically significant difference, similarly (p<0.05). We are of the opinion that the resistive index of the posterior capsular artery of the prostate gland is a parametric indicator to determine the severity of the benign prostatic hyperplasia and to assess the efficacy of the treatment with alpha-blocker medications.

Keywords:

Benign prostatic hyperplasia, transrectal colour doppler ultrasound, international prostate symptom score, prostatıc capsular artery resistive index,

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