Wan Mohd Nuzul Hakimi Wan SALLEH, Mohd Azlan NAFİAH, Shamsul KHAMİS, Salam Ahmed ABED

Chemical composition and lipoxygenase inhibitory activity of Alseodaphne peduncularis Meisn. essential oil

This study examined the chemical composition of the essential oil extracted from the bark of Alseodaphne peduncularis Meisn. (Lauraceae) by hydrodistillation with 0.2% yield. The essential oil was chemically characterised by gas chromatography-flame ionization detector and gas chromatography-mass spectrometry, and 31 constituents comprising 94.3% of the total oil content were identified. These constituents included β-caryophyllene (24.5%), viridiflorol (12.3%), δ-cadinene (9.8%), and bicyclogermacrene (4.2%), respectively. The tested essential oil showed moderate in vitro lipoxygenase activity with an IC50 = 60.2 μg/mL. To the best of our knowledge, there is no report and study on the bark part of this species.

Keywords:

Lauraceae, Alseodaphne peduncularis essential oil, hydrodistillation, GC-MS, lipoxygenase,

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