Nilay Şengül SAMANCI, Emir ÇELİK, Ezgi DEĞERLİ, Kerem ORUÇ, Şahin BEDİR, Sümeyra DERİN, Nihan ŞENTÜRK ÖZTAŞ, Zeynep Hande TURNA, Fuat Hulusi DEMİRELLİ, Melih KASAP, Burç Çağrı POYRAZ

FACTORS OF AFFECTING SLEEP QUALITY IN CANCER PATIENTS

Aim: Sleep disorders are one of the most common problems in patients with malignancy and they severely decrease the quality of life.We sought to investigate the frequency of sleep disturbances, its quantity, quality and possible correlation with related factors such asdepression and anxiety.Materials and Methods: 150 patients participated and the Pittsburgh Sleep Quality Index was used to evaluate the sleep quality. It is aself-administered questionnaire and standardized measure of sleep quality. Total score of ≥5 shows that the quality of sleep isremarkably bad. Also a self-report measure of depression, the Beck Depression Inventory (BDI); and a self-report measure of anxiety,Beck Anxiety Inventory (BAI) were used.Results: Of the 150 patients, 74.0% has bad sleep quality (score >5 ). Mean PSQI total score was 7.34 (min 0-max 20). No differenceswere found between PSQI mean scores in terms of gender, radiotherapy (RT), chemotherapy (CHT), having chronic disease or havingmetastatic disease. NSAIDs and opioids were significantly correlated with PSQI (p

Kanser Hastalarında Uyku Kalitesini Etkileyen Faktörler

yazıda, kanser hastalarında uyku bozukluklarının sıklığını, miktarını, kalitesini, depresyon ve anksiyete gibi ilişkili faktörlerle olası korelasyonunu araştırmaya çalıştık. Materyal ve Metot: Uyku kalitesini değerlendirmek için 150 hasta katıldı ve Pittsburgh Uyku Kalitesi İndeksi anketi kullanıldı. Bu anket kendi kendine uygulanan ve uyku kalitesinin standartlaştırılmış bir ölçüsüdür. Toplam ≥5 skoru uyku kalitesinin oldukça kötü olduğunu göstermektedir. Ayrıca depresyonun bir öz bildirim ölçüsü olan Beck Depresyon Envanteri (BDI); ve kaygı özgeçmiş ölçüsü Beck Anksiyete Envanteri (BAI) kullanıldı. Bulgular: 150 hastanın% 74.0'ında uyku kalitesi kötü idi (skor> 5). Ortalama PSQI toplam skoru 7.34 (min. 0-max 20) idi. PSQI ortalama skorları arasında cinsiyet, radyoterapi (RT), kemoterapi (CHT), kronik hastalığı olan veya metastatik hastalığı olanlarda fark bulunmadı. NSAID'ler ve opioidler PSQI ile anlamlı korelasyon gösterdi (p

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1. Passik S.D, Whitcomb L.A, Kirsh K.L ,Theobald D.E. An unsuccessful attempt to develop a single-item screen for insomnia in cancer patients. Journal of Pain and Symptom Management 2003: 25; 284-7.

2. Steindorf K, Clauss D, Tjaden C, Hackert T, Herbolsheimer F, Bruckner T, et al. Quality of Life, Fatigue, and Sleep Problems in Pancreatic Cancer Patients—A Randomized Trial on the Effects of Exercise . Dtsch Arztebl Int. 2019 ;116:471- 8.

3. Mollayeva T, Thurairajah P, Burton K, Mollayeva S, Shapiro CM, Colantonio A. The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep MedN Rev. 2016 ;25:52-73.

4. Ağargün MY, Kara H, Anlar O. Pittsburgh Uyku Kalitesi İndeksi’nin Geçerliği ve Güvenirliği. Turk Psikiyatri Derg 1996;7:107- 11.

5. Beck S.L, Schwartz A.L, Towsley G, Dudley W, Barsevick A. Psycho- metric evaluation of the Pittsburgh Sleep Quality Index in cancer patients. Journal of Pain and Symptom Management 2004 ;27:140-8.

6. de Kock I, Mirhosseini M, Lau F, Thai V, Downing M, Quan H, et al. Conversion of Karnofsky Performance Status (KPS) and Eastern Cooperative Oncology Group Performance Status (ECOG) to Palliative Performance Scale (PPS), and the interchangeability of PPS and KPS in prognostic tools. J Palliat Care. 2013 ;29:163-9.

7. Morris JL, Rohay J, Chasens ER. Sex Differences in the Psychometric Properties of the Pittsburgh Sleep Quality Index. J Womens Health (Larchmt). 2018 ;27 :278-82.

8. Wang YP, Gorenstein C. Psychometric properties of the Beck Depression Inventory- II: a comprehensive review. Braz J Psychiatry. 2013 ;35:416-31.

9. Julian LJ. Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care Res (Hoboken). 2011;63 :467-72.

10. Savard J, Laroche L, Simard S, Ivers H, Morin C.M. Chronic insomnia and immune functioning. Psychosomatic Medicine 2003; 65, 211-21.

11. Carpenter JS, Andrykowski MA. Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 1998;45: 5-13.

12. Forter BV, Stepanski EJ, Wang SC, Kasprowicz S, Durrence HH. Sleep and quality of life in breast cancer patients. J Pain Symptom Manage 2002;24: 471-80.

13. Savard J, Morin CM. Insomnia in the context of cancer: a review of a neglected problem. J Clin Oncol 2001; 19:895-908.

14. Harrington JJ1, Lee-Chiong T Jr. Sleep and older patients. Clin Chest Med. 2007 ;28 :673-84.

15. Byles JE, Mishra GD, Harris MA. The experience of insomnia among older women. Sleep 2005;28: 972-9.

16. Davidson JR, MacLean AW, Brundage MD, Schulze K. Sleep disturbance in cancer patients. Soc Sci Med 2002;54: 1309- 21.

17. Mercadante S, Girelli D, Casuccio A.Sleep disorders in advanced cancer patients: prevalence and factors associated. Support Care Cancer. 2004 May;12(5):355-9.

18. Theobald DE. Cancer pain, fatigue, distress, and insomnia in cancer patients. Clin Cornerstone 2004;6 ;15-21.

19. Murphy PJ, Badia P, Myers BL, Boecker MR, Wright KP Jr. Nonsteroidal anti-inflammatory drugs affect normal sleep patterns in humans. Physiol Behav. 1994;55:1063-6.

20. Roth T, Drake C. Evolution of insomnia: currents status and future direction. Sleep Med 2004;5: 23-30.

21. Buysse DJ. Insomnia, depression and aging Assessing sleep and mood interactions in older adults. Geriatrics 2004;59: 47- 51.

22. Kuo H.H., Chiu M.J., Liao W.C., Hwang S.L. Quality of sleep and related factors during chemotherapy in patients with stage I/II breast cancer. Journal of the Formosan Medical Association. 2006; 105: 64-9.