Bedriye KOYUNCU SÖKMEN, Tolga ŞAHİN, Alihan ORAL, Erdem KOÇAK

Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates

Aim: The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection ofdonor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in thedetection of HS in live liver donor candidates.Materials and Methods: Two hundred twenty-six healthy individuals who were admitted to Demiroğlu Bilim University as donor candidates for LTwere included in the study. Demographic, histopathological, laboratory and imaging findings of the donors were retrospectively reviewed. Computedtomography (CT) and magnetic resonance imaging (MRI) scans of the donors were retrospectively reevaluated and liver fat measurements wererecorded.Results: 39% (88) of the patients were female and 61% (138) were male. In the study population, the mean age was 34.3±8.7 years, the meanweight was 78.0±12.6 kg, the mean height was 169.1±9.6 cm, and the mean body mass index was 27.2±4.0. 42% of donors had 5% HS in liver biopsy. Both CT and MRI showed significant correlations with biopsy in HS detection (p

Canlı Karaciğer Donör Adaylarında Hepatosteatozun Saptanmasında Biyopsi, Bilgisayarlı Tomografi ve Manyetik Rezonans Görüntülemenin Karşılaştırılması

Amaç: Karaciğer donöründe hepatosteatoz (HS) varlığı, karaciğer transplantasyonu sonuçları üzerinde olumsuz etkilere sahiptir. Bu nedenle, donörde HS’nin tespiti, nakil öncesi dönemde hayati önem taşımaktadır. Bu çalışmanın amacı, canlı karaciğer donör adaylarında HS’nin saptanmasında karaciğer biyopsisi ve radyolojik yöntemlerin etkinliğini karşılaştırmaktır. Gereç ve Yöntem: Demiroğlu Bilim Üniversitesi’ne karaciğer transplantasyonu için donör adayı olarak kabul edilen 226 sağlıklı birey çalışmaya dahil edildi. Donörlerin demografik, histopatolojik, laboratuvar ve görüntüleme bulguları retrospektif olarak incelendi. Donörlerin bilgisayarlı tomografi (BT) ve manyetik rezonans görüntüleme (MRG) taramaları geriye dönük olarak yeniden değerlendirildi ve karaciğer yağ ölçümleri kaydedildi. Bulgular: Hastaların %39’u (88) kadın, %61’i (138) erkekti. Çalışma popülasyonunda ortalama yaş 34,3±8,7 yıl, ortalama ağırlık 78,0±12,6 kg, ortalama boy 169,1±9,6 cm ve ortalama vücut kitle indeksi 27,2±4,0 idi. Karaciğer biyopsisinde donörlerin %42’sinde %5 HS vardı. Hem BT hem de MRG, HS saptamada biyopsi ile anlamlı korelasyon gösterdi (p

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