Atilla Karateke, Raziye Kurt, Mehmet Dede, Ayhan Gül, Çetin Kılıç, Defne Özkaya

KLİNİĞİMİZE BAŞVURAN MOL GEBELİK OLGULARININ RETROSPEKTİF İNCELENMESİ: 5 YILLIK KLİNİK DENEYİM

Amaç: Bu çalışmada kliniğimizde molar gebeliktanısıyla tedavi edilen hastaların verilerikullanılarak gestasyonel trofoblastik hastalıklarıninsidansını belirlemeyi amaçladık.Gereç ve yöntem: Ocak 2009 ve Ocak 2014 yıllarıarasında kliniğimizde molar gebelik tanısı almışhastaların dosyaları retrospektif olarak incelendi.Hastaların yaş, gravida, parite ve abortus bilgilerikaydedildi. Olguların hikayesi, ultrasonografibulguları, β HCG ile birlikte laboratuar değerleri,histopatoloji sonuçları, tedavi yöntemleri ve takipteβ HCG değerleri kayıt edildi.Bulgular: Kliniğimizdeki molar gebelik insidansı1000 doğumda 5 olarak bulundu. Hastalarınortalama yaşı 28.72 ±7,5 olup ortalama gestasyonelyaş 10±2,4 haftaydı. β HCG değerleri 240 ile145100 arasında değişmekteydi. Hastaların20’sinde (%33.3) ultrason bulgusu molar gebelik ileuyumlu izlenmişti. Patoloji sonuçları 45 (%75)hastada parsiyel mol, 12 (%20) hastada kompletmol ve 3 (%5) hastada koryokarsinom gelmiştir.Olgularda hastalık ve komplikasyonlarına ait ölümolgusuna rastlanmamıştır.Sonuç: Kliniğimizde gestasyonel trofoblastikhastalık insidansı 1000 doğumda 5 olup daha kesinbir insidansa ulaşmak için ileri düzeyde araştırmalaryapılması gerekmektedir.

Anahtar Kelimeler:

Gestasyonel trofoblastik hastalık, insidans, MOL

A retrospective study of molar pregnancy cases submitted to our clinic: 5 years clinical experience

Aim: In this study, we aimed to determine the incidence of gestational trophoblastic disease by using data of patients who were treated for molar pregnancies. Material and methods: . The patients diagnosed as gestational trophoblastic disease between January 2009- January 2014 was evaluated retrospectively. Patients’ age, gravidity, parity and aborts were noted. Patients’ history, ultrasonographic findings, β HCG and laboratory results, hystopathology findings, treatment modalities and β HCG for following-up were recorded. Results: The incidence of molar pregnancy was found as 8 per 1000 deliveries. The mean age of patients was 28.72 ±7,5 and mean gestastional week was 10±2,4. β HCG values was found between 240 and 145100. Out of all patients, 20 (33.3%) had ultrasonographic signs of molar pregnancy. Pathology results revealed partial mole in 45 (75%), complete mole in 12 (20%) patients and choriocarcinoma in 3 (5%) patients. No mortality related to disease and complications was observed

Keywords:

Gestational Trophoblastic Disease, incidence, retrospective,

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