Mehmet CANİKLİOĞLU, Volkan SELMİ, Sercan SARI, Ünal ÖZTEKİN, Muharrem ÖZKAYA, Levent IŞIKAY

Böbrek fonksiyon bozukluğu olan hastalarda endoskopik üreter taşı cerrahisinin glomerüler filtrasyon hızı üzerine etkisi

Amaç: Ameliyat öncesi tahmini glomerüler filtrasyon oranları (eGFR) düzeyi 60 ml/dk’nın altında olan bir hasta grubunda üst üreter taşlarında üreterorenoskopi (URS) ya da fleksible üreterorenoskopi (fURS) öncesi ve sonrası eGFR değişimini ve buna etki eden faktörleri değerlendirmeyi amaçladık. Yöntem: Üst üreter taşı nedeniyle ameliyat planlanan ve kısa MDRD formülü ile hesaplanan ameliyat öncesi eGFR 60 ml/dk’nın altında olan 32 hasta çalışmaya dahil edildi. Hastaların ameliyat öncesi ve sonrası eGFR değişimlerine etki eden faktörler çoklu lineer regresyon analizi ile karşılaştırıldı. Bulgular: Düşük renal rezervli hastalar da tedavi sonrasında renal fonksiyonlar açısından iyi düzeyde bir iyileşme gösterdiler. Yaş, beden kitle indeksi (BKİ) ve preoperatif eGFR anlamlı düzeyde postoperatif eGFR’yi etkiliyordu (p

Anahtar Kelimeler:

Endoskopik üreter taşı tedavisi, Üreterorenoskopi, Retrograd intrarenal cerrahi, Glomerüler filtrasyon hızı, Düşük renal rezerv, Kronik böbrek yetmezliği

Effect of endoscopic ureteral stone surgery on glomerular filtration rate in patients with renal impairment

Objective: We aimed to evaluate the estimated glomerular filtration rates (eGFR) change in upper ureteral stones before and after ureterorenoscopy (URS) or flexible ureterorenoscopy (fURS) in a patient group with preoperative eGFR level below 60 ml / min and the factors affecting it. Methods: Thirty-two patients who were scheduled for surgery due to upper ureteral stones and whose preoperative eGFR that calculated with the short MDRD formula, below 60 mL / min were included in the study. Factors that affect preoperative and postoperative eGFR changes of the patients were investigated by multiple linear regression analysis. Results: Patients with low renal reserve also showed a good improvement in renal function after treatment. Age, body mass index (BMI) and preoperative eGFR significantly affected postoperative eGFR (p

Keywords:

Endoscopic ureteral stone treatment, Ureterorenoscopy, Retrograde intrarenal surgery, Glomerular filtration rate, Low renal reserve, Chronic renal failure,

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