Türkiye'de Bir Üniversite Hastanesi Dermatoloji Kliniğine Başvuran Vitiligo Hastalarının Klinik Bulguları

Vitiligo, dünya nüfusunun yaklaşık %1'ini etkileyen yaygın bir hastalıktır. Bu çalışmanın amacı vitiligo hastalarının epidemiyolojik verilerini, komorbid hastalıkları ve çeşitli kan parametrelerini değerlendirmektir. Bu çalışma retrospektif olarak yapıldı. Hasta kayıtları hastanenin elektronik veri tabanından tarandı. Verilerin dağılımına göre tanımlayıcı istatistikler ortalama ± standart sapma veya ortanca ve çeyrekler arası değerler olarak verildi. Kategorik değişkenler sayı ve yüzde olarak özetlendi. İstatistiksel analizler Jamovi programı ile yapıldı ve istatistiksel analizlerde anlamlılık düzeyi (p değeri) olarak p <0.05 kabul edildi. Çalışmaya 30'u (%44.1) erkek, 38'i (%55.9) kadın olan 68 kişi katıldı. Komorbid hastalıklar 22 (%32,4) hastada tespit edildi. 15 (%22.1) hastada tiroid hastalığı, 12 (%17.6) hastada tiroid otoantikorları pozitif bulundu. Hastalık alevlenmeleri (p=0.025) ve stres öyküsü kadınlarda daha sıktı (p=0.011). Strese bağlı alevlenme öyküsü kadınlarda ve 18 yaşından büyük hastalarda daha sık görüldü. Bu nedenle, özellikle vitiligolu kadınlarda psikolojik faktörlerin değerlendirilmesi ve gerektiğinde psikiyatriste danışılması önemlidir.

Anahtar Kelimeler:

Stres, Tiroid otoantikorları, Vitiligo

Clinical Findings of Vitiligo Patients Attending a University Hospital Dermatology Clinic in Turkey

Vitiligo is a common disorder which affects about 1% of the world population. The aim of this study was to evaluate the epidemiological data, comorbid diseases, and several blood parameters of the vitiligo patients. This study was performed as a retrospective chart review. Patient records were screened from the electronic database of the hospital. Descriptive statistics were given as mean ± standard deviation or median and interquartile ranges according to the distribution of the data. Categorical variables were summarized as number and percentage. Statistical analyses were performed with Jamovi program and p<0.05 was accepted as significance level (p value) in statistical analyses. This study included 68 individuals, 30 (44.1%) of whom were males, and 38 (55.9%) of whom were females. Comorbid diseases were detected in 22 (32.4%) patients. Thyroid diseases were present in 15 (22.1%) patients, and thyroid autoantibodies were positive in 12 (17.6%) patients. Exacerbations of disease were more frequent in females (p=0.025), and history of stress was also more frequent in females (p=0.011). History of stress related exacerbations were more frequent in females and patients older than 18 years of age. Therefore, it is important to evaluate psychological factors especially in women with vitiligo and to consult to a psychiatrist when necessary.

Keywords:

Stress, Thyroid autoantibodies, Vitiligo,

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