Süleyman Cemil OĞLAK, Ilgın TÜRKÇÜOĞLU, Şeyhmus TUNÇ

İn Vitro Fertilizasyon ile Gebe Kalan Hastaların Gebelik Sonuçlarının Değerlendirilmesi: Tersiyer Merkez Deneyimi

Bu çalışmada in vitro fertilizasyon (IVF) ile gebe kalan hastaların gebelik sonuçlarının retrospektif olarak değerlendirilmesi amaçlanmıştır. Nisan 2009 ile Şubat 2013 tarihleri arasında doğum yapan 6369 gebenin kaydı retrospektif olarak değerlendirildi. Kontrollü Ovaryan Hiperstimulasyon-IVF/ICSI ile gebe kalan 151 olgu ile çalışma grubu oluşturuldu. Kontrol grubu kendiliğinden gebe kalan hastalardan sistematik örnekleme ile seçilerek oluşturuldu (262 olgu). Her iki grubun sonuçları değerlendirildi. Çalışma grubunda çoğul gebelik, preterm doğum, preterm prematür membran rüptürü, malprezentasyon, gestasyonel diyabet oranları daha fazlaydı. Ortalama doğum haftası ve ortalama doğum ağırlığı kontrol grubunda daha fazlaydı. Her iki grupta yenidoğanın kan gazı pH değerleri, 1. ve 5. dakika Apgar skoru açısından istatistiksel farklılık yoktu. Yenidoğan yoğun bakım ünitesine yatış oranı ve perinatal ölüm oranı çalışma grubunda daha fazlaydı. Yardımcı üreme teknikleri ile meydana gelen gebeliklerde maternal ve fetal riskler daha fazladır. Tüm bu riskler gebelik sürecinin ve yenidoğanın yakın takibini gerektirmektedir.

Anahtar Kelimeler:

Çoğul Gebelik, Erken Doğum, Perinatal Ölüm

Evaluation of Pregnancy Results of in Vitro Fertilization Patients: A Tertiary-Center Experience

In this study, we aimed to retrospectively evaluate the pregnancy outcomes of in vitro fertilization (IVF) patients. The records of 6369 pregnant women who gave birth between April 2009 and February 2013 were evaluated retrospectively. 151 Patients who were conceived Controlled Ovarian Hyperstimulation-IVF/ICSI were included in the study group. The control group was formed by a systematic sampling of spontaneous pregnant cases (262 cases). The results of both of the groups were evaluated. Multiple pregnancies, preterm delivery, preterm premature rupture of membranes, malpresentation, and gestational diabetes rates were significantly higher in the study group. Mean gestational week at birth and mean birth weight was significantly higher in the control group. There was no statistically significant difference in blood pH values and Apgar score of the 1 and 5 minutes of the newborn in both groups. Neonatal intensive care unit admission and perinatal mortality rates were significantly higher in the study group. Both maternal and fetal risks are increased in pregnancies with assisted reproductive techniques. All these risks require close monitoring of the mother and newborn during pregnancy and the postpartum period.

Keywords:

Multiple Pregnancy, Preterm Birth, Perinatal Death,

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