Coronary artery ectasia (CAE) is an abnormality of the coronary anatomy and might be a variant of the Coronary Artery Disease (CAD). The CAE can cause angina pectoris and even MI with vasospasm, dissection, or thrombus in patients without CAD. Isolated CAE is defined as CAE without significant coronary artery stenosis. The mechanisms responsible for ectasia formation are not clearly known. However, the histopathological changes in CAE are shown to be similar to the changes that are observed in atherosclerotic lesions and they include intimal–medial degeneration and hyalinization. There is no current guideline for percutaneous coronary angioplasty in stenotic ectatic coronary arteries due to variations in coronary anatomy. We report successful simultaneous double balloon angioplasty in a patient who had coronary artery ectasia.