Ibuprofen has been using for postoperative pain relief for many years. The bilateral superficial cervical plexus block has been performed for thyroid surgery safely and effectively. We propose to compare them regarding postoperative opioid consumption and pain scores. A total of 60 patients was randomized into two groups. The Ibuprofen group (Group I , n=30) recieved 800 mg intravenous ibuprofen in 100 mL saline 15 minutes before general anesthesia induction. The patients who randomized for bilateral superficial cervical plexus block group (Group S, n=30) were performed a bilateral superficial cervical plexus block group. Opioid consumption, pain scores, and side effects were recorded and data were analysed. The fentanyl consumption during 48 hours after surgery with PCA device was recorded. No significant difference was found. The mean pain scores were recorded at 30 min, 1 h, 2 h, 4 h, 8 h, 12 h, 24 h and 48 h after surgery. No significant difference was found at the first 8 hours between two groups. However, there was statistically significant difference at 12, 24 and 48th hours. No significant difference was found regarding adverse effects in both groups. Both ibuprofen and bilateral superficial cervical plexus block are used for post-thyroidectomy pain in the literature. Ibuprofen has promising effect on postoperative pain relief and opioid consumption. A single dose ibuprofen may prevent pain as successful as bilateral superficial cervical plexus block for 8 hours after surgery..
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Mutlu V, Ince I. Preemptive intravenous ibuprofen application reduces pain and opioid consumption following thyroid surgery. Am J Otolaryngol. 2019;40:70-3.
Joshi GP, Ogunnaike BO. Consequences of inadequate postoperative pain relief and chronic persistent postoperative pain. Anesthesiol Clin North Am 2005;23:21-36.
Medscape: First Databank – Adverse effects list Fentanyl, 2004 .https:// emedicine.medscape.com › article › 287790
Stessel B, Boon M, Pelckmans C, at al. Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial. Eur J Anaesthesiol. 2019;36:351-9.
Mayhew D, Sahgal N, Khirwadkar R, at al. Analgesic efficacy of bilateral superficial cervical plexus block for thyroid surgery: meta-analysis and systematic review. Br J Anaesth. 2018;120:241-51.
Gurkan Y, Tas Z, Toker K, at al. Ultrasound guided bilateral cervical plexus block reduces postoperative opioid consumption following thyroid surgery. J Clin Monit Comput. 2015;29:579–84.
Gürkan Y, Yörükoğlu HU, Işık E, at al. The Effect of Ibuprofen on Postoperative Opioid Consumption Following Total Hip Replacement Surgery. Turk J Anaesthesiol Reanim. 2019;47:31-4.
Cashman JN. The mechanisms of action of NSAIDs in analgesia. Drugs. 1996;52 Suppl 5:13-23.
Andrieu G, Amrouni H, Robin E, at al. Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia. Br J Anaesth. 2007;99:561–6.
Dieudonne N, Gomola A, Bonnichon P, at al. Prevention of postoperative pain after thyroid surgery: a double-blind randomized study of bilateral superficial cervical plexus blocks. Anesth Analg. 2001;92:1538–42.
Shih ML, Duh QY, Hsieh CB, at al. Bilateral superficial cervical plexus block combined with general anesthesia administered in thyroid operations. World J Surg. 2010;34:2338–43.