Nasal septum and sphenoid sinus located adenoid cystic carcinoma

Adenoid cystic carcinoma (ACC) is a rare tumor comprising 1% of malignant tumors of head and neck . The most common localization for ACC is minor salivary glands and involvement of sphenoid sinus is very rare. It grows slowly and has a high tendency of local recurrence, and perineural invasion. Surgery and postoperative radiotherapy is considered as an optimal treatment. We present a case of 50-year-old female with complaint of nasal obstruction. The computed tomography imaging showed the presence of nasal mass arising from the posterior part of the nasal septum and the adjoining sphenoid sinus anterior wall. The mass was excised and the pathologic specimens revealed ACC with perineural invasion, positive surgical margin and bone destruction. The patient recieved postoperative radiotherapy. Improved treatment outcomes led the investigators to recommend the postoperative radiation as the routine treatment approach for most patients with the ACC of the head and neck to improve local control rates

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1. Gill KS, Frattali MA. An Unusual Presentation of Adenoid Cystic Carcinoma. Case Rep Otolaryngol. 2015;2015:826436.

2. Bruzgielewicz A, Osuch-Wójcikiewicz E, Majszyk D, Chęciński P, Nyckowska J, Zawadzka B, Skowrońska-Gardas A,Niemczyk K. Adenoid cystic carcinoma of the head and neck-a 10 years experience. Otolaryngol Pol. 2011;65(5 Suppl):6–11.

3. DeMonte F, Ginsberg LE, Clayman Gl. Primary Malignant Tumors of the Sphenoid Sinus. Neurosurgery. 2000;46(5):1084-91.

4. Belaldavar BP, Batra R. Adenoid cystic carcinoma of the nasal septum: a rare case report. J Sci Soc. 2013;40(1):39-40.

5. Amit M, Binenbaum Y, Sharma K, Ramer N, Ramer I, Agbetoba A, Miles B, Yang X, Lei D, Bjoerndal K, Godballe C8, Mücke T, Wolff KD, Fliss D, Eckardt AM, Copelli C, Sesenna E, Palmer F, Patel S, Gil Z. Adenoid cystic carcinoma of the nasal cavity and paranasal sinuses: a meta-analysis. J Neurol Surg B Skull Base. 2013;74(3):118-25.

6. Gondivkar SM, Gadbail AR, Chole R, Parikh RV. Adenoid cystic carcinoma: a rare clinical entity and literature review. Oral Oncol. 2011;47(4):231-6.

7. Garden AS, Weber RS, Morrison WH, et al. The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation. Int J Radiat Oncol Biol Phys. 1995;32(3):619–26.

8. Gomez DR, Hoppe BS, Wolden SL, Ang KK, Peters LJ. Outcomes and prognostic variables in adenoid cystic carcinoma of the head and neck: a recent experience. Int J Radiat Oncol Biol Phys. 2008;70(5):1365-72.

9. Silverman DA, Carlson TP, Khuntia D, Bergstrom RT, Saxton J, Esclamado RM. Role for postoperative radiation therapy in adenoid cystic carcinoma of the head and neck. Laryngoscope. 2004;114(7):1194-9.

10. Zhang Q, Yang L, Yang AK, Guo ZM. Clinical study on 88 cases of adenoid cystic carcinoma in nasal cavity and paranasal sinuses”. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009;44(4):311-4.

11. Liu W, Xu Z, Tang P. Clinical analysis of 42 cases with adenoid cystic carcinoma of the nasal cavity. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011;25(12):548-50.

12. Ellington CL, Goodman M, Kono SA, Grist W, Wadsworth T, Chen AY, Owonikoko T, Ramalingam S, Shin DM, Khuri FR,Beitler JJ, Saba NF. Adenoid cystic carcinoma of the head and neck. Cancer. 2012;118(21): 4444–51.

13. Giridhar P, Mallick S, Laviraj MA, Bhasker S. Adenoid cystic carcinoma sphenoid sinus with intracranial extension treated by radical radiotherapy: a rare case. Eur Arch Otorhinolaryngol. 2015;272(4):1037-40.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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