Gonul Varan KOC, Neşe Ersöz GÜLÇELİK, CAVİT ÇULHA, Esra CİVGİN², Muzaffer ÇAYDERE, Yalçın ARAL

İntratiroidal Ektopik Timus Olgusu

Ektopik intratiroidal timus dokusu nadir görülmektedir. Daha çok çocukluk çağında, asemptomatik tiroid nodülü olarak saptanmaktadır. Benign veya malign tiroid nodulleri ile karışabilmektedir. İlerleyen yaşla birlikte tıpkı timus dokusu gibi regrese olabilmektedir. Ektopik timus dokusunda çok nadiren timoma ve timus karsinomu geliştiği bildirilmiştir. İntratiroidal ektopik timus dokusu, timus benzeri ultrasonografik görüntü özelliği ile akılda bulundurulmalı ve gereksiz işlemlerden kaçınılmalıdır.

A Case of Intratyhroidal Ectopic Thymus

Ectopic intrathyroidal thymus tissue is rare. Mostly it is seen in childhood as an asymptomatic thyroid nodule. It can be easily misdiagnosed as a benign or malignant thyroid nodule. Like thymus, it may regress in time. Ectopic thymus tissue can rarely develop to thymoma or thymic carcinoma. Intrathyroidal ectopic thymus tissue has similar sonographic features to thymus and should be kept in mind to avoid unnecessary diagnostic and surgical intervention.

PDF

___

1. Tovi F, Mares AJ. The aberrant cervical thymus:embryology, pathology, and clinical implications. Am J Surg. 1978;136(5):631-7.
2. Carpenter GR, Emery JL. Inclusions in human thyroid. J Anat. 1976;122(Pt 1):77-89.
3. Bale PM, Sotelo-Avila C. Maldescent of thymus: 34 necropsy and 10 surgical casee, including 7 thymuses medial to the mandible. Pediatr Pathol. 1993;13(2):181-90.
4. Kim HG, Kim MJ, Lee MJ. Sonographic appearance of intrathyroidal ectopic thymus in children. J Clin Ultrasound. 2012;40(5):266-71.
5. Nasseri F, Eftekhari F. Clinical and radiologic review of normal and abnormal thymus: pearls and pitfalls. Radiographics. 2010;30(2):413-28.
6. Kara T, Tepe M. Bilateral aberran servikal timusun ultrasonografik bulguları. Causapedia. 2013;2:510.
7. Zielke AM, Swischuk LE, Hernandez JA. Ectopic cervical thymic tissue:can imaging obviate biopsy and surgical removal?. Pediatr Radiol. 2007;37(11):1174-7.
8. Tunkel DE, Erozan YS, Weir EG. Ectopic cervical thymic tissue diagnosis by fine needle aspiration. Arch Pathol Lab Med. 2001;125(2):278-81.
9. Han BK, Yoon HK, Suh YL. Thymic ultrasound. II. Diagnosis of aberrant cervical thymus. Pediatr Radiol. 2001;31(7):480-7.
10. Fitoz S, Atasoy C, Türköz E, Gümüş D, Erden I, Akyar S. Sonographic findings in ectopic cervical thymus in an infant. J Clin Ultrasound. 2001;29(9):523-6.
11. Park HP, Ryu CW, Kim GY, Shim KS. Intrathyroidal thymic tissue mimicking a malignant thyroid nodule in a 4-year-old child. Ultrasonography. 2014;33(1):71-3.
12. Segni M, di Nardo R, Pucarelli I, Biffoni M. Ectopic intrathyroidal thymus in childrean: a long-term follow-up study. Horm Res Paediatr. 2011;75(4):258-63.
13. Sang LW, Deepali G, Connelly J. Adult ectopic thymus adjacent to thyroid and parathyroid. Arch Pathol Lab Med. 2001;125(6):842-3.
14. Mardi K. Sharma J. Ectopic intrathyroidal thymus-rare finding in adult. The internet Jornal of Head and Neck Surgery. 2008;3(1):1-4.
15. Yao W, Chen CH, Lee JJ, Chen BF, Liu TP. Ectopic thymic carcinoma in the neck. Ann Thorac Surg. 2010;90(2):666-8.
16. 16. Schloegel LJ, Gottschall AJ. Ectopic cervical thymus: is empric surgical excision necessary?. Int J Pediatr Otorhinolaryngol. 2009;73(3):475-9.