İhsan AKSOY, Mehmet Hamdi ÖRÜM

Haloperidol decanoate-induced acneiform eruption: A case report

ISSN: 2147-0634
Yayın Aralığı: 4
Başlangıç: 2012
Yayıncı: Effect Publishing Agency ( EPA )

Haloperidol decanoate is a depot preparation of haloperidol, which may rarely cause dermatological side effects among other commonly seen side effects. A PubMed search did not reveal any report of acneiform drug eruption associated with haloperidol decanoate in English literature, although it is listed as a side effect by the manufacturer. We report a case of bipolar disorder patient with manic episode who developed acneiform lesions after treatment with haloperidol decanoate 300 mg for psychotic symptoms, and it subsided two weeks of injection of the drug.

PDF

___

Arndt K, Jick H. Rates of cutaneous reaction to drugs. A report from Boston collaborative drug surveillance program. JAMA. 1976;235:918-22.

Lange-Asschenfeldt C, Grohmann R, Lange-Asschenfeldt B, et al. Cutaneous adverse reactions to psychotropic drugs: data from a multicenter surveillance program. J Clin Psychiatry. 2009;70:1258-65.

Maharaj K, Gunmacher LB, Moeller R. Haloperidol decanoate: injection site reactions (Iener). J Clin Psychiatry. 1995;56:172-3.

Du-Thanh A, Kluger N, Bensalleh H, et al. Drug-induced acneiform eruption. Am J Clin Dermatol. 2011;12:233-45.

Heng MC. Lithium carbonate toxicity: acneiform eruption and other manifestations. Arch Dermatol. 1982;118:246-8.

Hesse S, Berbis P, Lafforgue P, et al. Acne and enthesiopathy during antiepileptic treatment. Ann Dermatol Venereol. 1992;119:655-8.

Mishra B, Praharaj SK, Prakash R, et al. Aripiprazole-induced acneiform eruption. Gen Hosp Psychiatry. 2008;30:479-81.