From multiple myeloma to leishmaniasis: The cause is fever!

From multiple myeloma to leishmaniasis: The cause is fever!

Leishmaniasis is a vector-borne parasitic disease that constitutes a major public health problem. Leishmaniasis presents with various clinical manifestations, from skin involvement to life-threatening visceral disease. Fever of unknown origin should be considered in the differential diagnosis. In this case, we describe a patient referred with a diagnosis of multiple myeloma, but ultimately diagnosed with leishmaniasis based on our evaluation, to draw attention to this disease.

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  • 1. Andrade-Narváez FJ, Vargas-González A, Canto-Lara SB, et al. Clinical picture of cutaneous leishmaniases due to Leishmania (Leishmania) mexicana in the Yucatan peninsula, Mexico. Mem Inst Oswaldo Cruz. 2001; 96:163–7.
  • 2. Bladé J. Clinical practice. Monoclonal gammopathy of undetermined significance. N Engl J Med. 2006;355:2765-70.
  • 3. Magill AJ. Leishmania species: Visceral (Kala-Azar), cutaneous, and mucosal leishmaniasis. In: Mandell GL, Bennet JE, Dolin R (eds.), Mandell, Douglas and Bennett’s principles and practice of infectious diseases. Churchill Livingstone, Philadelphia; 2015;3091–107.
  • 4. Randi ML, Ruzzon E, Tezza F, et al. Monoclonal gammopathy in human leishmaniasis. Neth J Med. 2006;64:50-1.
  • 5. Rombola F, Spinoso A, Bertuccio SN. Monoclonal gammopathy after visceral leishmaniasis: Just a coincidence? Infez Med. 2008;16:173-4.
  • 6. Garcia-Menendez L, Santamaria Lopez C, Fernandez Eroles AL, et al. Monoclonal component in visceral leishmaniasis: A rare association that can lead to misdiagnosis. Rev Clin Esp. 1998;198:517-20.
  • 7. Gabrielli GB, Zaia B, Stanzial AM, et al. Visceral leishmaniasis: A rarely diagnosed disease in northern Italy. Report of a case. Ann Ital Med Int. 2001;16:185-91.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )