Analysis of keratometric and optical biometric measurements in patients with allergic conjunctivitis before and after the treatment of topical 0.2 % olopatadine

To determine the optical biometric measurements of patients with allergic conjunctivitis before and after topical 0.2% olopatadine treatment using autokerato-refractometry and optical biometry. In this prospective study, 96 eyes of 48 patients with allergic conjunctivitis were examined. All participants had a detailed ophthalmic examination including best-corrected visual acuity (BCVA), intraocular pressure (IOP), anterior, posterior segment examination using slit-lamp biomicroscopy, autokerato- refractometric, and optical biometry measurements (including spherical and cylindrical values, keratometry, corneal astigmatism with axis, axial length and anterior chamber depth) before and one month after topical 0.2% olopatadine treatment. The mean age of 48 patients (31 women, 17 men) with allergic conjunctivitis was 26.3 ± 16.2 years (6-76). While the pre-treatment autokerato-refractometric measurements showed cylindrical aberration in 79.8% of the patients, this ratio in the post-treatment period was 65.6%. The comparisons of the classification of maximum astigmatism and corneal astigmatism in both visits were statistically significant (p=0.000, p=0.003 respectively). However, the classification of corneal astigmatism obtained with optical biometry was similar (p=0.10). The measurements of maximum astigmatism and keratometry recorded by autokerato-refractometry, and anterior chamber depth showed a significant decrease after the treatment. We determined that the values of cylindrical aberration, keratometry, anterior chamber depth, and the sort of astigmatism may change after the acute phasis of allergic conjunctivitis. So, while prescribing spectacles, we should review all these factors.

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