The aim of the current study was to assess efficacy and safety of ab interno trabeculectomy surgery applied with trabectome device in early period. The study was designed among the 30 eyes of 26 patients who had undergone trabectome surgery with the diagnosis of open-angle glaucoma. Patients were evaluated as retrospectively in terms of preoperative and postoperative intraocular pressure (IOP), number of drugs used and complications. While the preoperative mean IOP was 28.78±5.57 mmHg (n:30) with the mean number of medications 3.40±1.04, the mean IOP was 18.24±5.54 mmHg (n:30) with the mean number of medications 0.90±1.27 at 1st month. At 3rd month the mean IOP was 16.37±3.36 mmHg (n:28) with the mean number of medications 0.70±1.10 and at 6th month the mean IOP was 16.51±3.80 mmHg (n:28) with the mean number of medications 1.13±0.96. When postoperative measurements compared with preoperative values, detected reductions in IOP and number of medications were statistically significant (p
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1. Tsai JC, Johnson CC, Dietrich MS. The Ahmed shunt versus the Baerveldt shunt for refractory glaucoma: a single-surgeon comparison of outcome. Ophthalmology. 2003;110(9):1814-21.
2. Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL; Tube versus Trabeculectomy Study Group.Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. Am J Ophthalmol. 2012;153(5):789-803.
3. Saheb H, Ahmed II. Micro-invasive glaucoma surgery: current perspectives and future directions. Curr Opin Ophthalmol. 2012;23(2):96-104.
4. Minckler D, Baerveldt G, Ramirez MA, Mosaed S, Wilson R, Shaarawy T, Zack B, Dustin L, Francis B. Clinical results with the Trabectome, a novel surgical device for treatment of open-angle glaucoma. Trans Am Ophthalmol Soc. 2006;104:40-50.
5. Francis BA, See RF, Rao NA, Minckler DS, Baerveldt G. Ab interno trabeculectomy: Development of a novel device (Trabectome) and surgery for open-angle glaucoma. J Glaucoma. 2006;15(1):68-73.
6. Nguyen QH. Trabectome: A novel approach to angle surgery in the treatment of glaucoma. Int Ophthalmol Clin. 2008;48(4):65–72.
7. Chihara E, Nishida A, Kodo M, Yoshimura N, Matsumura M, Yamamoto M, Tsukada T. Trabeculotomy ab externo: an alternative treatment in adult patients with primary open-angle glaucoma. Ophthalmic Surg. 1993;24(11):735-9.
8. Barkan O. Surgery of congenital glaucoma; review of 196 eyes operated by goniotomy. Am J Ophthalmol. 1953;36(11):1523-34.
9. Ichhpujani P.,Moster MR. Novel Glaucoma Surgical Devices, Dr Shimon Rumelt Ed.Glaucoma - Basic and Clinical Concepts, InTech, 2011,C:20:417-42.
10. Minckler DS, Baerveldt G, Alfaro MR, Francis BA. Clinical results with the Trabectome for treatment of open-angle glaucoma. Ophthalmology. 2005;112(6):962-7.
11. Minckler D, Mosaed S, Dustin L, Ms BF; Trabectome Study Group.Trabectome (trabeculectomy- internal approach): additional experience and extended follow-up. Trans Am Ophthalmol Soc. 2008;106:149-59.
12. Ting JLM, Damji KF, Stiles MC;Trabectome Study Group. Ab interno trabeculectomy: Outcomes in exfoliation versus primary open-angle glaucoma. J Cataract Refract Surg. 2012;38(2):315-323.
13. Ahuja Y, Ma Khin Pyi S, Malihi M, Hodge DO, Sit AJ. Clinical Results of Ab Interno Trabeculotomy Using the Trabectome for Open-Angle Glaucoma: The Mayo Clinic Series in Rochester, Minnesota, Am J Ophthalmol. 2013;156(5):927–35.
14. Altan-Yaycioglu R, Canan H, Pelit A, Akova YA.. Intraocular pressure after phacoemulsification in eyes with pseudoexfoliation. J Cataract Refract Surg. 2009;35(5):952–4
15. Mosaed S. The First Decade of Global Trabectome Outcomes, Clin Surg Ophthalmol. 2014;32;21-9.
16. Francis BA. Trabectome Combined with phacoemulsification versus phacoemulsification alone: a prospective, non-randomized controlled surgical trial. Clin Surg Ophthalmol. 2010;28:1-7.
17. Francis BA, Winarko J. Combined Trabectome and cataract surgery versus combined trabeculectomy and cataract surgery in open-angle glaucoma. Clin Surg Ophthalmol. 2011;29:4–10.
18. Francis BA, Dustin L, Kawji S, Yeh J, Sit A, Mosaed S, Johnstone M. Combined cataract extraction and trabeculotomy by the internal approach for coexisting cataract and open-angle glaucoma: initial results. J Cataract Refract Surg. 2008;34:1096-1103.
19. Mosaed S, Rhee DJ, Filippopoulos T, Tseng H, Deokule S, Weinreb RN Trabectome outcomes in adult open-angle glaucoma patients: One-year follow-up. Clin Surg Ophthalmol. 2010;28;5-9.
20. Jea SY, Mosaed S, Vold SD, Rhee DJ. Effect of a failed trabectome on subsequent trabeculectomy. J Glaucoma. 2012;21(2):71-5.
21. Ahuja Y, Malihi M, Sit AJ. Delayed-onset symptomatic hyphema after ab interno trabeculotomy surgery. Am J Ophthalmol. 2012;154(3):476–80.
22. Filippopoulos T, Rhee DJ. Novel surgical procedures in glaucoma: Advances in penetrating glaucoma surgery. Curr Opin Ophthalmol. 2008;19(2):149–54.
23. Vold SD. Ab Interno Trabeculotomy With the Trabectome System:What Does the Data Tell us? Int Ophthalmol Clin. 2011;51(3):65-8.