Could mean platelet volume be a useful marker for infectious diseases? a review of literature

Mean platelet volume (MPV), a parameter of complete blood count analysis, measures the average size of platelets. The alterations of MPV levels have been described as a diagnostic or prognostic predictor in patients with infectious diseases including sepsis, infective endocarditis, pneumonia, brucellosis, cellulitis, acute pyelonephritis, ascites fluid infection, hepatitis B or hepatitis C in recent studies. Although some matters still remain unclear, it can be said that MPV, especially in a scoring system, may be a cost-effective and useful marker for monitoring and predicting outcomes in patients with some infectious diseases in the future

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Tekin M, Konca C, Gulyuz A, Uckardes F, Turgut M. Is the mean platelet volume a predictive marker for the diagnosis of acute pyelonephritis in children? Clin Exp Nephrol. 2015;19(4):688-93.

Abdel-Razik A, Eldars W, Rizk E. Platelet indices and inflammatory markers as diagnostic predictors for ascitic fluid infection. Eur J Gastroenterol Hepatol. 2014;26(12):1342-7.

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Hu Y, Lou Y, Chen Y, Mao W. Evaluation of mean platelet volume in patients with hepatitis B virus infection. Int J Clin Exp Med. 2014;7(11):4207-13.

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Sharma K, Yadav A. Association of Mean Platelet Volume with Severity, Serology & Treatment Outcome in Dengue Fever: Prognostic Utility. J Clin Diagn Res. 2015;9(11):EC01-3.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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