Adem Keskin, Recai Aci, Utku Duran, Melek Bilgin, Göksenin Ünlügüzel Üstün, Mukadder Erdem

Koronavirüs Hastalığında Hastalık Şiddeti ve Enflamasyonla İlgili Göstergeler Arasındaki İlişki

Amaç: Koronavirüs hastalığı-2019 (COVID-19) servis ve yoğun bakım ünitelerinde takip edilen hastaların tam kan parametreleri ile enflamatuvar süreçte hastalığın prognozu açısından önemli olan biyokimyasal biyobelirteçlerin değerleri retrospektif olarak incelendi. Gereç ve Yöntemler: Bu çalışmaya, COVID-19 yoğun bakımda yatan 130 hasta ve COVID-19 serviste yatan 147 hasta dahil edilmiştir. Ayrıca çalışmaya, kontrol grubu olarak sağlıklı 47 birey eklenmiştir. Bu hastaların ve bireylerin tam kan parametreleri [WBC (beyaz kan hücresi), lenfosit, monosit, nötrofil, trombosit, nötrofil/lenfosit(NLR), monosit/lenfosit (MLR)] ile C-reaktif protein (CRP), prokalsitonin, ferritin, eritrosit sedimantasyon oranı (ESR) ve albümin değerleri retrospektif olarak incelendi. Elde edilen laboratuvar sonuçları karşılaştırıldı. Bulgular: Yoğun bakımda yatan hastaların prokalsitonin, CRP, ESR, WBC, nötrofil, NLR, MLR, ferritin ve prokalsitonin ortalama değerleri, hem serviste yatan hastalardan hem de kontrol grubundan daha yüksekti (p

The Relationship Between Inflammatory Indicators and the Severity of the Disease in Coronavirus Disease

Objective: The complete blood count parameters and biochemical biomarkers important for the follow-up of patients in the inflammatory process of coronavirus disease 2019 (COVID-19) inpatients in the ward, and intensive care were analysed retrospectively. Materials and Methods: One hundred thirty inpatients in the intensive care and 147 inpatients in the COVID-19 ward were included in this study. Additionally, 47 healthy people were added as a control group. Whole blood parameters [white blood cell (WBC), lymphocyte, monocytes, platelet, neutrophil, monocyte/ lymphocyte (MLR), neutrophil/lymphocyte (NLR)], ferritin, C-reactive protein (CRP), procalcitonin, erythrocyte sedimentation ratio (ESR) and albumin values of these patients and individuals were analyzed retrospectively. Obtained laboratory values were compared. Results: The procalcitonin, CRP, ESR, WBC, neutrophil, NLR, MLR, ferritin and procalcitonin values of the patients the intensive care patients were higher than the other two groups (p

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