HİPOSPADİAS TÜBÜLARİZASYONUNDA KULLANILAN ÇİFT VERTİKAL İNSİZYON HANGİ DERİNLİKTE OLMALIDIR?
AMAÇ:Tübülarizasyon, özellikle hipospadias olmak üzere lümen gerektiren organların cerrahisinde kullanılantekniklerden biridir. Bu çalışmada çift vertikal insizyon ile oluşturulan tüplerde insizyon derinliğinin yaraiyileşmesi ve lümen genişliğine olan etkileri araştırılmıştır.GEREÇ veYÖNTEMLER:Yedi adet New Zealand tavşanda her bir tavşan üzerinde 3 adet derin 3 adet yüzeyelçift vertikal insizyon içeren toplam 42 adet tüp oluşturduk. Postoperatif 3., 5. ve 21. günlerde her bir tavşandan biryüzeyel, bir derin insizyonla yapılan tüp olmak üzere ikişer adet tüp çıkarıldı. Tüpler hematoxylin-eosin veMasson's trichrome ile boyandı ve inflamasyon, fibrozis ve lümen çapları açısından incelendi. Gruplar arasıparametrelerin karşılaştırılması için Mann-Whitney tek yönlü varyans analizi ve Kruskal-Wallis testi kullanıldı.İstatistiksel anlamlılık için P0.05)SONUÇ:Çalışmamızda derin insizyon ile yüzeyel insizyon arasında histopatolojik incelemede ve lümençaplarının değerlendirilmesinde anlamlı fark olmaması, aynı lümen genişliğine yüzeyel çift vertikal insizyon ileulaşılabilmesi çift vertikal yüzeyel insizyon ile tübülarizasyonun uygulanabilir bir teknik olduğunu göstermektedir
How Deep Should The Double Vertical Incision Used In Tubularization For Hypospadias Be?
OBJECTIVE: Tubularization is one of the techniques used in surgery of luminal organs and especially for hypospadias. In this study, the effects of incision depth on wound healing and luminal dimensions were investigated. MATERIALand METHODS: Seven New Zealand rabbits were used. On the skin of each rabbit, 6 tubes were constructed (3 were with deep incision and 3 were superficial) with a total of 42 for the experiment. On postoperative days 3, 5 and 21, one tube with deep incision and one with superficial incision were removed from the each rabbit. The tubes were stained with hematoxylin-eosine and Masson's trichrome dyes. They were examined for inflammation, fibrosis and luminal diameters. Mann-Whitney U variance analysis and Kruskal- Wallis tests were used for statistical analysis. P0.05). CONCLUSION: Since there is no significant difference for histopathological examination and luminal diameter between groups with deep and superficial vertical incisions, and to be able to achieve similar luminal diameters with double superficial vertical incisions, tubularization with double superficial vertical incisions is suggested to be applicable to hypospadias surgery.
___
- 1. BelmanAB. Hypospadias and chordee. In: BelmanAB,
King LR, Kramer SA, editors. Clinical pediatric
urology, 4th edition, London: Martin Dunitz, 2002:
1061-1092.
- 2. Ehrlich RM, Alter GJ: Reconstructive and plastic
surgery of the external genitalia. Philadelphia,
Saunders, 1999:14-22.
- 3. Snodgrass WT. Tubularized incised plate hypospadias
repair: indications, technique, and complications.
Urology. 1999;54(1):6-11.
- 4. Baskin LS, Ebbers MB. Hypospadias: anatomy,
etiology, and technique. J Pediatr Surg 2006;41(3):463-72.
- 5. Borer JG, Bauer SB, Peters CA, Diamond DA, Atala A,
Cilento BG Jr, Retik AB. Tubularized incised plate
urethroplasty: expanded use in primary and repeat
surgery for hypospadias. J Urol 2001;165(2):581-5.
- 6. Stein R, Schröder A, Thüroff JW. Use of buccal
mucosa in urethral surgery. Urologe A
2007;46(12):1657-63.
- 7. Barbagli G, Morgia G, Lazzeri M. Retrospective
outcome analysis of one-stage penile urethroplasty
using a flap or graft in a homogeneous series of
patients. BJU Int 2008;102(7):853-60.
- 8. Aminsharifi A, Taddayun A, Assadolahpoor A, Khezri
A. Combined use of Mathieu procedure with plate
incision for hypospadias repair: a randomized clinical
trial.Urology2008;72(2):305-8.
- 9. Snodgrass W. Tubularized, incised plate urethroplasty
for distal hypospadias. J Urol 1994;151(2):464-5.
- 10. Yazici M, Copcu E, Etensel B, Culhaci N, Balkaya M,
Ozkisacik S, Gursoy H. Comparison of double vertical
incision with various tubularization techniques and its
clinical application. Urol Int 2003;71(3):299-305.
- 11. Kolon TF, Gonzales ET Jr. The dorsal inlay graft for
hypospadias repair. J Urol 2000;163(6):1941-3.
- 12. Steckler RE, Zaontz MR. Stent-free Thiersch-Duplay
hypospadias repair with the Snodgrass modification. J
Urol 1997;158(3 Pt 2):1178-80.
- 13. Rich MA, Keating MA, Snyder HM, Duckett JW.
Hinging the urethral plate in hypospadias meatoplasty.
J Urol 1989 Dec;142(6):1551-3.
- 14. Retik AB, Borer JG. Primary and reoperative
hypospadias repair with the Snodgrass technique.
World J Urol 1998;16(3):186-91.
- 15. Elicevik M, Tireli G, Sander S. Tubularized incised
plate urethroplasty: 5 years' experience. Eur Urol
2004;46(5):655-9.
- 16. Snodgrass W, Koyle M, Manzoni G, Hurwitz R,
Caldamone A, Ehrlich R. Tubularized incised plate
hypospadias repair: results of a multicenter experience.
J Urol 1996156(2 Pt 2):839-41.
- 17. Stehr M, Lehner M, Schuster T, Heinrich M, Dietz HG.
Tubularized incised plate (TIP) urethroplasty
(Snodgrass) in primary hypospadias repair. Eur J
Pediatr Surg 2005;15(6):420-4.
- 18. Mustafa M. The concept of tubularized incised plate
hypospadias repair for different types of hypospadias.
Int Urol Nephrol 2005;37(1):89-91.
- 19. Anwar-ul-Haq, Bader I, Akhter N, Abbasi Z.
Tubularized incised plate urethroplasty of
hypospadias. J Coll Physicians Surg Pak
2004;14(8):489-91.
- 20. Snodgrass W, Koyle M, Manzoni G, Hurwitz R,
Caldamone A, Ehrlich R. Tubularized incised plate
hypospadias repair for proximal hypospadias. J Urol
1998;159(6):2129-31.
- 21. Luo CC, Lin JN. Repair of hypospadias complications
using the tubularized, incised plate urethroplasty. J
Pediatr Surg 1999;34(11):1665-7.
- 22. DiSandro M, Palmer JM. Stricture incidence related to
suture material in hypospadias surgery. J Pediatr Surg
1996;31(7):881-4.
- 23. Retik AB, Keating M, Mandell J. Complications of
hypospadias repair. Urol Clin North Am
1988;15(2):223-36.
- 24. Snodgrass W. Does tubularized incised plate
hypospadias repair create neourethral strictures? J Urol1999;162(3 Pt 2):1159-61.
- 25. Bleustein CB, Esposito MP, Soslow RA, Felsen D,
Poppas DP. Mechanism of healing following the
Snodgrass repair. J Urol 2001;165(1):277-9.
- 26. Lopes JF, Schned A, Ellsworth PI, Cendron M.
Histological analysis of urethral healing after
tubularized incised plate urethroplasty. J Urol
2001;166(3):1014-7.
- 27. Scherz HC, Kaplan GW, Boychuk DI, Landa HM,
Haghighi P. Urethral healing in rabbits. J Urol
1992;148(2 Pt 2):708-10.