Zeliha ÜNLÜ, Gülgün YILMAZ, Aslıhan ULUSOY

Coexistence of Diffuse Idiopathic Skeletal Hyperostosis and Late-Onset Ankylosing Spondylitis in a Sixty-year-old Patient

Diffüz idiyopatik skeletal hiperostozis (DİSH) ve ankilozan spondilit (AS) aksiyel iskelet ve periferik bölgelerde birbirlerinden farklı patolojiler sonucunda gelişen, ligaman ve tendonlarda ossifikasyon ile karakterize iki ayrı hastalıktır. DİSH ve AS birlikteliği nadir görülen bir durumdur ve İngilizce literatürde de bu duruma dikkat çeken olgu sayısı oldukça azdır. Bu olgu sunumunda sakroileit varlığı yönünden AS, dorsolomber omurga grafi bulguları yönünden ise DİSH için tipik görünüme sahip olan ve İnsan (human) lökosit antijeni-B27 negatif bir olgu sunuldu. Olgunun semptomlarının geç başlangıçlı olması, her iki hastalığın birbirleri ile etkileşimi ve bu durumun prognoza etkisi literatür ışığında tartışıldı.

Diffüz İdiyopatik Skeletal Hiperostozis ve Geç Başlangıçlı Ankilozan Spondilit Birlikteliği Altmış Yaşında Bir Olgu

Diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) are two diseases characterized by ossification of the ligaments and tendons in both the axial skeleton and peripheral sites with very different pathologies. Coexistence of DISH and AS is a rare condition and there are relatively few cases in the English-language literature. In this paper, we report a human leukocyte antigen-B27-negative patient who presented with the typical appearance of DISH on the dorsal radiograph and also had sacroileitis, suggesting AS. We discussed prognosis of the late-onset case and the interaction of two diseases in this coexistence.

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