Abdur RAUF, Şengül UYSAL, Taibi BEN HADDA, Bina Shaheen SIDDIQUI, Haroon KHAN, Muhammad Atif KHAN, Muhammad IJAZ, Mohammad S. MUBARAK, Saud BAWAZEER, Tareq ABU-IZNEID, Ajmal KHAN, Umar FAROOQ

Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan

The purpose of present research was to examine the antibacterial, cytotoxic, and phytotoxic profiles of three important Pakistani medicinal plants viz., Teucrium stocksianum, Chenopodium botrys, and Micromeria biflora. The antibacterial, cytotoxicity, and phytotoxicity activities of samples extracted from these plants were evaluated by a modified agar well-diffusion method, brine shrimps cytotoxic assay, and Lemna acquinoctialisbased phytotoxic assay, respectively. Results revealed marked susceptibility of both the crude extracts and the aqueous fractions of these plants against K. pneumonia and B. subtilis. Methanolic extracts and aqueous fractions exhibited significant cytotoxicity in a concentration-dependent manner. Similarly, an outstanding phytotoxic effect was observed for the extracts/ fractions. Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.

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