Hypoglycemia causes alterations in consciousness such as confusion and stupor, as well as seizure and sudden hemiparesis.In this article, neurologic manifestations of acute hypoglycemia and probable causes have been reviewed in connection with two cases encountered.The first patient developed orofasciobuccal and upper limb dyskinetic movements while the second patient displayed transient hypoglycemic hemiplegia.The dyskinetic movements are attributed to the increase of glutamate which is the excitatory neurotransmitter in the striatum, particularly in the caudate nucleus. It is also presumed that the transient hypoglycemic hemiplegia is due to hemodynamic alterations in corticalVatershed areas?