The relation between aortic pulse pressure and coronary artery disease

Amaç: Nabız basıncı (NB) kardiyovasküler mortalitenin önemli bir belirtecidir. Ta­nısal amaçlı koroner anjiyografi (KAG) uygulanan hastalarda aortik NB ile koroner arter hastalığı (KAH) varlığı ve yaygınlığı arasındaki ilişki araştırılmıştır.Hastalar ve Metod: Çalışma grubu 550 hastadan oluşmuştur (363 erkek, 187 kadın). Hastalar NB

Aortik nabız basıncı ile koroner arter hastalığı arasındaki ilişki: Koroner anjiyografik çalışma

Objective: Pulse pressure (PP) is a significant marker of cardiovascular morbid­ity.We investigated the relation between aortic PP and the presence and extent of coronary artery disease (CAD) in patients undergoing diagnostic coronary an­giography (CAG).Patients and Method: The study group consisted of 550 patients (363 men, 187 women).We evaluated patients in two different groups, PP < 60 mmHg and ≥ 60 mmHg. Results: In univariate analysis gender and presence of hyperlipidemia showed no statistically significant differences between both groups. However, the ratio of patients having diabetes mellitus, hypertension or smoking were significantly higher in ≥ 60 mmHg PP group. The mean age was 55.2 ±11.9 in < 60 mmHg PP group and 61.3±9.3 in the other group (p

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  • 1. Madhavan S, Ooi Wl, Cohen H, Alderman MH. Relation of pulse pressure and blood pressure reduction to the incidence of myocardial infarction. Hypertension 1994;23:395–401.
  • 2. Benetos A, Safar M, Rudnichi A, Smulyan H, Richard JL, Ducimetiere P, et al. Pulse pressure: a predictor of long-term cardiovascular mortality in a French male population. Hypertension 1997;30:1410–5.
  • 3. Mitchell GF, Moye LM, Braunwald E, Rouleau J-L, Bernstein V, Geltman EM, Flaker GC, Pfeffer MA. Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function: SAVE Investigators. Circulation 1997;96:4254–60.
  • 4. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Pede S, Porcellati C. Ambulatory pulse pressure: a potent predictor of total cardiovascular risk in hypertension. Hypertension 1998;32:983–8.
  • 5. Chae CU, Pfeffer MA, Glynn RJ, Mitchell GF, Taylor JO, Hennekens CH. Increased pulse pressure and risk of heart failure in the elderly. JAMA 1999;281:634–9.
  • 6. Franklin SS, Khan SA, Wong ND, Larson MG, Levy D. Is pulse pressure useful in predicting risk for coronary heart disease?: The Framingham Heart Study. Circulation 1999;100:354-60.
  • 7. Millar JA, Lever AF, Burke V. Pulse pressure as a risk factor for cardiovascular events in the MRC mild hypertension trial. J Hypertens 1999;17:1065-72.
  • 8. Fang J, Madhavan S, Alderman MH. Pulse pressure: a predictor of cardiovascular mortality among young normotensive subjects. Blood Press 2000;9:260-6.
  • 9. Sesso HD, Stampfer MJ, Rosner B, Hennekens CH, Gaziano JM, Manson JE, et al. Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in men. Hypertension 2000;36:801–7.
  • 10. Blacher J, Staessen JA, Girerd X, Gasowski J, Thijs L, Liu L, et al. Pulse pressure not mean pressure determines cardiovascular risk in older hypertensive patients. Arch Intern Med 2000;160:1085-9.
  • 11. Safar ME, Lévy BI, Struijker-Boudier H: Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases. Circulation 2003;107:2864–9.
  • 12. Danchin N, Benetos A, Lopez-Sublet M, Demicheli T, Safar M, Mourad JJ, on behalf of the ESCAPP Investigators. Aortic pulse pressure is related to the presence and extent of coronary artery disease in men undergoing diagnostic coronary angiography: a multicenter study. Am J Hypertens 2004;17:129-33.
  • 13. Lee TM, Lin YJ, Su SF, Chien KL, Chen MF, Liau CS, et al. Relation of systemic arterial pulse pressure to coronary atherosclerosis in patients with mitral stenosis. Am J Cardiol 1997;80:1035-9.
  • 14. Philippe F, Chemaly E, Blacher J, Mourad JJ, Dibie A, Larrazet F, et al. Aortic pulse pressure and extent of coronary artery disease in percutaneous transluminal coronary angioplasty candidates. Am J Hypertens 2002;15:672-7.
  • 15. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003;289:2560-72.
  • 16. Dodge HT, Sandler H, Ballew DW, Lord JD Jr. The use of biplane angiography for yje measurement of left ventricular volume in man. Am Heart J 1960;60:762-6.
  • 17. Weber KT. Metabolic responses of extracellular matrix in tissue repair. Ann Med 1997;29:333-8.
  • 18. Kelly R, Tunin R, Kass D. Effect of reduced aortic compliance on left ventricular contractile function and energetics in vivo. Circ Res 1992;71:490–502.
  • 19. Watanabe H, Ohtsuka S, Kakihana M, Sugishita Y. Coronary circulation in dogs with an experimental decrease in aortic compliance. J Am Coll Cardiol 1993;21:1497-506.
  • 20. Stefanadis C, Wooley CF, Bush CA, Kolibash AJ, Boudoulas H. Aortic distensibility abnormalities in coronary artery disease. Am J Cardiol 1987;59:1300-4.
  • 21. Kingwell BA, Waddell TK, Medley TL, Cameron JD, Dart AM. Large artery stiffness predicts ischemic threshold in patients with coronary artery disease. J Am Coll Cardiol 2002;40:773-9.
  • 22. Schram MT, Kostense PJ, Van Dijk RA, Dekker JM, Nijpels G, Bouter LM, Heine RJ, Stehouwer CD. Diabetes, pulse pressure and cardiovascular mortality: the Hoorn Study. J Hypertens 2002;20:1743-51.
  • 23. Benetos A, Rudnichi A, Safar M, Guize L. Pulse pressure and cardiovascular mortality in normotensive and hypertensive subjects. Hypertension 1998;32:560-4.
  • 24. Zakopoulos NA, Lekakis JP, Papamichael CM, Toumanidis ST, Kanakakis JE, Kostandonis D, et al. Pulse pressure in normotensives: a marker of cardiovascular disease. Am J Hypertens 2001;14:195-9.
  • 25. Jankowski P, Kawecka-Jaszcz K, Czarnecka D, Brzozowska-Kiszka M, Ponik-Urbaska A, Styczkiewicz K. Ascending aortic blood pressure-derived indices are not correlated with the extent of coronary artery disease in patients with impaired left ventricular function. Atherosclerosis 2006;184:370-6.
  • 26. Ryan SM, Waack BJ, Weno BL, Heistad DD. Increases in pulse pressure impair acetylcholine-induced vascular relaxation. Am J Physiol 1995;268(1 Pt 2):H359-63.
  • 27. Christensen KL. Reducing pulse pressure in hypertension may normalize small artery structure. Hypertension 1991;18:722-7.
Koşuyolu Heart Journal-Cover
  • ISSN: 2149-2972
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1990
  • Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi
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