Harun KUNDİ, Murat GÖK, Emrullah KIZILTUNÇ, Mustafa ÇETİN

Oldukça Nadir Görülen Tetanoz Aşısının Neden Olduğu Tip 1 Kounis Sendromu

Patolojik mekanizması mast hücrelerinin degranülasyonuna bağlı hassas kişilerde görülen akut miyokardiyal enfarktüsü Kounis sendromu olarak tanımlanır. Biz burada tetanoz aşısı sonrası akut koroner sendrom ile başvuran bir Kounis sendromu bildirdik. Ek olarak, tüm olası sebepler özellikle de iskemi dışlandı.

Anahtar Kelimeler:

Allerjik kalp krizi, Kounis sendromu, tetanoz aşısı

A Rarely Seen Type-I Kounis Syndrome Caused By Tetanus Vaccine

The pathogenesis mechanism of Kounis syndrome is defined by mast-cell degranulation that has been amplified to induce acute myocardial infarction in susceptible individuals. Here, we report a case of Kounis syndrome presented with acute coronary syndrome after a tetanus vaccine. In addition, all possible other etiologies, especially ischemia, were excluded.

Keywords:

Allergic myocardial infarction, Kounis syndrome, tetanus vaccine,

PDF

___

1. Kounis NG, Grapsas ND, Goudevenos JA. Unstable angina, allergic angina, and allergic myocardial infarction. Circulation 1999;100:e156-e.
2. Kounis NG, Zavras GM. Allergic angina and allergic myocardial infarction. Circulation 1996;94:1789.
3. Tavil Y, Turfan M, Türkoğlu S, Abacı A. Kounis syndrome secondary to amoxicillin/clavulanic acid use. Int J Cardiol 2008;124:e4-e7.
4. Cervellin G, Neri G, Lippi G, Curti M, Kounis NG. Kounis syndrome triggered by a spider bite. A case report. Int J Cardiol 2016.
5. Goto K, Kasama S, Sato M, Kurabayashi M. Myocardial scintigraphic evidence of Kounis syndrome: what is the aetiology of acute coronary syndrome? Eur Heart J 2015:ehv703.
6. Nikolaidis LA, Kounis NG, Gradman AH. Allergic angina and allergic myocardial infarction: a new twist on an old syndrome. The Canadian Journal of Cardiology 2002;18:508-11.
7. Kounis NG. Kounis syndrome (allergic angina and allergic myocardial infarction): a natural paradigm? Int J Cardiol 2006;110:7-14.
8. Genovese A, Spadaro G. Highlights in cardiovascular effects of histamine and HI-receptor ansgonists. Allergy 1997;52:67-78.
9. Kounis NG, Mazarakis A, Tsigkas G, Giannopoulos S, Goudevenos J. Kounis syndrome: a new twist on an old disease. Future Cardiology 2011;7:805-24.