Mutlu BÜYÜKLÜ, Eftal Murat BAKIRCI, Hüsnü DEĞİRMENCİ, Gökhan CEYHUN, Ergün TOPAL

Kontrast Madde Nefropatisi: Antioksidan Tedavi Yönetimi

Günümüzde görüntüleme ve girişimsel işlemlerin artış göstermesi ile birlikte kontrast madde kullanımı giderek artmıştır. Oksidatif stresin kontrast madde nefropatisi patofizyolojisinde önemli rolü vardır. Çeşitli önleyici tedaviler ve yan etkisi daha az düşük osmolar kontrast maddelere rağmen, klinik pratikte tek önleyici tedavi intravenöz iztonik infüzyonudur. Bu yüzden yeni bir koruyucu tedaviye ihtiyaç vardır.

Anahtar Kelimeler:

Kontrast, kontrast madde nefropatisi, antioksidan tedavi, anjiyografi

Contrast-Induced Nephropathy: Management by Antioxidant Therapy

At present, the number of imaging and interventional procedures using contrast agents is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Despite the use of various prophylactic therapies and low-osmolar contrast agents with lesser adverse effects, intravenous isotonic fluid infusion is the only method that has been proven to be effective in preventing contrast-induced nephropathy in clinic practice. Therefore, a novel kidney-protecting treatment model is required for contrast-induced nephropathy.

Keywords:

Contrast, contrast-induced nephropathy, antioxidant treatment, angiography,

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi