İskemide Yeni Bir Marker: İskemi Modifiye Albumin

İskemi modifiye albumin iskemi sonucu oluşan reaktif oksijen türevlerinin yol açtığı albuminde modifikasyon ile oluşur. Albumin kobalt bağlama testi kullanılarak ölçülür. Bu test geçici olmayan kardiyak hasarın başlangıcından önce iskeminin erken saptanmasında kullanılır. Bu yazıda iskemi modifiye albuminin patofizyolojisi, analizi ve klinik uygulamalarını inceledik.

A New Marker for Ischemia: Ischemia-modified Albumin

Ischemia-modified albumin constitutes via a modifcation in albumin where reactive oxygen species are formed due to ischemia. Albumin is measured using the cobalt binding test, and this test is used for the determination of albumin prior to the development of permanent cardiac injuries. In this review, we investigated the pathophysiology, analysis and clinical utility of ischemia-modified albumin.

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Koşuyolu Heart Journal-Cover
  • ISSN: 2149-2972
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1990
  • Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi
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