Mehmet Ramazan ŞEKEROĞLU, Erdem ÇOKLUK, Selcuk YAYLACI, Ali Fuat ERDEM, Fatıma Betül TUNCER, Hamad DHEİR, Ertuğrul GÜÇLÜ, Aziz ÖĞÜTLÜ, Deniz ÇEKİÇ, Abdülkadir AYDIN, Fatma Behice SERİNKAN CİNEMRE

COVID-19'da Tiyol-Disülfid Dengesi: Tam Kan Sayımı Parametreleri ile İlişkisinin Değerlendirilmesi

Amaç: Bu çalışmada, COVID-19 hastalarında tiyol-disülfid homoeostazı ile hemogram parametreleri arasındaki ilişkiyi değerlendirmeyi amaçladık. Gereç Yöntem: Total tiyol (TT), Native tiyol (NT), dinamik disülfid durumu (DDS), DDS / NT, DDS / TT, NT / TT oranı ve CBC parametreleri COVID-19 pozitif 68 hasta ve 31 sağlıklı bireyde analiz edildi. Bulgular: Kontrol grubunda TT, NT, DD, hemoglobin ve hematokrit düzeyleri hasta gruplarına göre daha yüksekti. Serviste tedavi gören COVID-19 hastalarının TT, NT, DD ve lenfosit seviyeleri yoğun bakım ünitesinde tedavi edilenlere göre daha yüksekti; WBC, nötrofil ve NLO düşüktü (P

Anahtar Kelimeler:

COVID-19, toplam tiyol, doğal tiyol, Dinamik Disülfür Durumu, Tam Kan Sayımı

Thiol-Disulphide Homoeostasis in COVID-19: Evaluation of its Relationship with Complete Blood Count Parameters

Objective: In this study, we aimed to evaluate the relationship between thiol-disulfide homoeostasis and hemogram parameters in COVID-19 patients. Methods: Total thiol(TT), Native thiol(NT), dynamic disulfide status(DDS), DDS/NT, DDS/TT, NT/TT ratio and CBC parameters were analyzed in 68 patients with positive COVID-19 and 31 healthy individuals. Results: TT, NT, DD, hemoglobin and hematocrit levels were higher in the control group than in patient groups. TT, NT, DD and lymphocyte levels of COVID-19 patients treated in medical floor were higher than those treated in intensive care unit; WBC, neutrophil and NLR were low(P

Keywords:

COVID-19, Total Thiol, Native Thiol, Dynamic Disulfide Status, Complete Blood Count,

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ISSN: 1309-3878
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 2009
Yayıncı: Düzce Üniversitesi Tıp Fakültesi Aile Hekimliği AD adına Yrd.Doç.Dr.Cemil Işık Sönmez