Analysis of Bone Mineral Density and Hip Fracture in Geriatric Patients with Heart Failure

Objective: Osteoporosis, identified by low Bone Mineral Density (BMD), is a progressive disease affecting especially older adults. Hip fracture is the important result of osteoporosis. Heart failure and osteoporosis are two common chronic conditions that are critical in healthcare of older adults. This study is aimed at evaluating bone mineral density and hip fractures in geriatric aged patients with heart failure. Methods: We retrospectively analyzed 157 geriatric patients with heart failure and 155 geriatric control subjects without any cardiovascular disease and risk factors. The results of transthoracic echocardiography, biochemical analysis and bone mineral densitometry results (DEXA) were evaluated from patient file data. Medical records of clinics provided the osteoporotic fracture history and operation for fracture, list of current and prior use of medications. Results: Among the 157 patients, 45 (29%) had normal BMD, 14 (9%) had osteopenia, and 98 (62%) had osteoporosis. In 155 control subjects, 68 (44%) had normal BMD, 12 (8%) had osteopenia, and 75 (46%) had osteoporosis (P=0.019). Sixteen subjects (10.2%) in heart failure group and 6 subjects (3.9%) in controls had hip fracture (p=0.029). Level of 25-hydroxy vitamin D was significantly lower in heart failure than in controls (p

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Newman AB, Gottdiener JS, Mcburnie MA, Hirsch CH, Kop WJ, Tracy R, et al. Associations of subclinical cardiovascular disease with frailty. J GerontolA Biol Sci Med Sci. 2001;56:M158-66.

Walston J, McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, et al. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med. 2002;162:2333-41.

Kenny AM, Waynik IY, Smith J, Fortinsky R, Kleppinger A, McGee D. Association between level of frailty and bone mineral density in community-dwelling men. J Clin Densitom. 2006;9:309-14.

Cankurtaran M, Yavuz BB, Halil M, Dagli N, Ariogul S. General characteristics, clinical features and related factors of osteoporosis in a group of elderly Turkish men. Aging Clin Exp Res. 2005;17:108-15

Wiktorowicz ME, Goeree R, Papaioannou A, Adachi JD, Papadimitropoulos E. Economic implications of hip fracture: health service use, institutional care and cost in Canada. Osteoporos Int. 2001;12:271–278.

Yesil Y, Ulger Z, Halil M, Halaclı B, Yavuz BB, Yesil NK, et al. Coexistence of osteoporosis (OP) and coronary artery disease (CAD) in the elderly: It is not just a by chance event. Arch GerontolGeriatr. 2012;54:473-6.

Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, et al. Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int. 1999;10:259-64.

van Diepen S, Majumdar SR, Bakal JA, McAlister FA, Ezekowitz JA. Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients. Circulation. 2008;118:1946-52

Carbone L, Buzková P, Fink HA, Lee JS, Chen Z, Ahmed A, et al. Hip fractures and heart failure: findings from the Cardiovascular Health Study. Eur Heart J. 2010;31:77-84.

Cetin M, Kozdağ G, Ural D, Kahraman G, Yılmaz I, Akay Y, et al. Could decreased vitamin D levels be related with impaired cardiac autonomic functions in patients with chronicheart failure: an observational study. Anadolu Kardiyol Derg. 2014;14:434-41.

Anagnostis P, Karagiannis A, Kakafika AI, Tziomalos K, Athyros VG, Mikhailidis DP. therosclerosis and osteoporosis: age-dependent degenerative processes or related entities? Osteoporos Int. 2009;20:197-207.

Eastell R, Newman C, Crossman DC. Cardiovascular disease and bone. Arch BiochemBiophys. 2010;503:78-83.

Manolagas SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010;31:266-300.
KONURALP TIP DERGİSİ-Cover
  • ISSN: 1309-3878
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2009
  • Yayıncı: Düzce Üniversitesi Tıp Fakültesi Aile Hekimliği AD adına Yrd.Doç.Dr.Cemil Işık Sönmez
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