Uçkun Sait UÇAN, Bilal Osamah MOHAMMED, Murat YİĞİT

Atlardan İzole Edilen Stenotrophomonas maltophilia Suşlarının Antibiyotik Direnci

Stenotrophomonas maltophilia gamma proteobacteria içerisinde yer alan ve hem insanlardan hem de hayvanlardan sık izole edilen bir bakteri türüdür. S. maltophilia’nin en dikkat çeken özelliklerinden birisi bakterinin intrinsik mekanizmalar da dahil olmak üzere çeşitli şekillerde geliştirdiği yüksek antibiyotik direncidir. Bu çalışma ile atlardan izole edilmiş olan S. maltophilia’nın timokionon ile çeşitli antibiyotiklerin beraber kullanıldıklarındaki etkileşimini ölçmek amaçlandı. Ne sinerjizm ne de antogonizm şeklinde bir etkileşim ölçülmedi. Ancak timokiononun S. maltophilia suşları üzerinde antibakteriyel etkisi tespit edildi..

Anahtar Kelimeler:

Stenotrophomonas maltophilia, Antibiyotik, at, direnç

Antibiotic Resistance of Stenotrophomonas maltophilia Strains Isolated from Horses

Stenotrophomonas maltophilia is a member of gamma proteobacteria that has been frequently isolated from humans as well as from animals. One of the most outstanding feature of S. maltophilia is its antibacterial resistance that is basicly controlled by various pathways including intrinsic manner. By this study we aimed to evaluate the interaction of S. maltophilia suspected equine strains with various antibiotics in the presence of Thymoquinone in vitro. Disc diffusion technique was used for measuring interactions between the thymoquinone and others. No measurable inhibition zone for synergistic or antagonistic effect between the thymoquinone and test antibiotics was observed. However, the thymoquinone itself has an antibacterial potential.

Keywords:

Stenotrophomonas maltophilia, Antibiotic, horse, resistance,

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