Çocuklarda İlaç Alerjileri
Bir ilacın profilaksi, tanı veya tedavi amacı ile kullanımı sırasında veya sonrasında
oluşan istenmeyen etkiler ilaç aşırı duyarlılık reaksiyonu (ADR), ilaç ters etkisi
veya ilaç reaksiyonu olarak tanımlanır. İlaç ADR yaşamı tehdit edebilecek durumlara
neden olabilmesi, hastanede yatış süresini uzatabilmesi, tedavi maliyetini artırabilmesi
nedeni ile önemli bir sağlık sorunudur.
Tanının en önemli kısmını dikkatli alınan bir anamnez oluşturur. Öncelikle reaksiyonun
ilaç alerjisi ile ilişkisi belirlenmeli, sonrasında da bu durumun immünolojik
reaksiyon mu yoksa nonimmün reaksiyon mu olduğuna karar verilmelidir. Öyküye
göre tanısal testler planlanmalıdır. İlaç alerjilerinin akut tedavisi suçlanan ilacın
kesilmesi ve aktif lezyonun durumuna göre gerekli destek medikal tedavi uygulanması
şeklindedir. Hastalarda uzun dönemli yaklaşım planı yapmak son derece önemlidir.
İlaç alerjisi olan hastalar akılcı ilaç kullanımı konusunda eğitilmelidir. Bu yazıda
çocuklarda ilaç alerjilerine yaklaşım güncel rehberler doğrultusunda değerlendirilecektir.
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