Alerjik Hastalıklarda Mikrobiyotanın Önemi

ÖzAlerjik hastalıklar dünya nüfusunun önemli bir kısmını etkilemektedir. Süt çocuklarında alerji sıklığı %10 birinci kuşak akrabalarında atopik zemin varsa %20-30’akadar yükselmektedir. Son yıllarda alerjik hastalıkların başlangıcı ve duyarlanmanın artmasında bağırsak florasının etkileri tartışılmaktadır. Flora immünolojik ve inflamatuvar sistemik yanıtı düzenliyor olabileceği fikri ile alerjik hastalıkların sıklığının artışı ile intestinal flora hipotezi ileri sürülmüştür. Bu derlemede alerjik hastalıklarda mikrobiyotanın rolü ile ilgili son gelişmeler özetlenmiştir.
Anahtar Kelimeler:

Alerji, Probiyotik, Mikrobiyota

The Importance of Microbiota in Allergic Diseases

AbstractAllergic diseases affect a significant part of the world population. The incidence of allergies in infancy is 10% but if there is an atopic background in the first generation relatives up to 20-30%. In recent years, the effects of intestinal flora have been debated in the onset of allergic diseases and in the increase of sensitization. The intestinal flora hypothesis has been proposed with the idea that flora may regulatethe immunological and inflammatory systemic response and the increased frequencyof allergic diseases. This review summarizes recent developments in the role of microbial in allergic diseases.

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