Erişkinlerde Pnömokok Bağışıklaması

Pnomokoklar primer olarak insan da hastalık yaparlar. Kaynak genellikle asemptomatiktaşıyıcıların nazofarenksleridir. Pnömokokların yaptığı klinik tablolar üst solunumyolu enfeksiyonlarından pnömoni, bakteriyemi ve menenjite kadar değişkenlik gösterir.Toplumdan edinilmiş pnömoniler de en sık bakteriyal etken pnömokoklardır. Pnömonive invazif pnömokokal hastalık tüm dünyada özellikle beş yaş altı çocuklar, 65 yaşüstü erişkinler ve risk grubunda tanımlanan kişiler de önemli bir mortalite ve morbiditenedenidir. Surveyans verilerinin ortaya koyduğu antibiyotik direnci özellikle penisilingrubu antibiyotiklere karşı %50 ye varan direnç artışı göz önüne alındığında koruyuculukönem kazanmaktadır. Bağışıklama en etkin koruyucu araçtır ve bugün erişkinlerdekullanımı onaylanmış olmak üzere iki tip aşı vardır: konjüge pnömokok aşısıve polisakkarid pnömokok aşısı. Bu derlemede erişkin popülasyonunda güncel pnömokokbağışıklama önerileri irdelenmeye çalışılmıştır.

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