Vücut Kitle İndeksinin Egzersiz Testi Sırasındaki Kan Basıncı Yanıtına Etkisi
Amaç: Egzersiz sırasında, vücut kitle indeksinin (VKI) arteryel kan basıncına etkisinin efor testi yapılan hastalarda değerlendirilmesidir. Yöntem: Bu retrospektif çalışmaya miyokard perfüzyon sintigrafisi normal olan 168 hasta alındı. Hastalar VKI’lerine göre 3 gruba ayrıldı; 18,5-24,9 (normal, grup 1), 25-29,9 (preobez, grup 2), 30-39 ( obez, grup 3). Egzersiz stres testinin 1., 3. ve 6. dakikalarında sistolik ( SKB) ve diastolik kan basıncı (DKB) değerleri ölçüldü. Klinik özellikler ve antropometrik ölçümler kaydedildi. Bulgular: Tüm grubun hem SKB ve DKB değerleri egzersiz ile birlikte anlamlı artış gösterdi (p < 0,01). Birinci, 3. ve 6. dakika ortalama SKB ve DKB değerleri dikkate alındığında, 6. dakika DKB değeri hariç, üç grupta da fark anlamlı bulundu (p < 0001). Üçüncü dakikada 1. dakikaya göre sistolik ve diastolik kan basıncı değişim yüzdesi istatististiksel olarak anlamlı bulunmadı (sırası ile p=0,454 ve p=0,196). Başlangıca göre 6. dakikadaki SKB artışının yüzdesinin ortalaması da farklı bulunmadı (p= 0,109). Sonuç: Egzersiz sırasında obezite ile kan basıncı artış oranlarında farklılık görülmemesi, obezitenin egzersize fizyolojik cevabı bozmadığını düşündürmektedir
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- Rezende FA, Rosado LE, Ribeiro Rde C, Vidigal Fde C, Vasques AC, Bonard IS, de Carvalho CR. Body mass index and waist circumference: association with cardiovascular risk factors. Arq Bras Cardiol. 2006 ;87(6):728-34.
- Da Silva AC, Rosa AA. Blood pressure and obesity of children and adolescents association with body mass index and waist circumference. Arch Latinoam Nutr. 2006;56(3):244-50.
- World Health Organisation. The AsiaPacific Perspective: Redefining obesity an itstreatment.(http//www.iotf.org/asiapacifi c)(15 Haziran 2007)
- Gibbons RJ. ACC/AHA Guidelines for exercise testing. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Exercise Testing). J Am Coll Cardiol 1997;30:260–315
- Bruce RA. Exercise testing methods and interpretation. Adv Cardiol 1978;24:6–15
- Charkodian N, Joyner MJ, Johnson CP, Eisenach JH, Dietz NM, Waalin BG. Balance between cardiac output and sympathetic nerve activity in resting humans: role in arterial pressure regulation. J. Physiol.2005; 568:315-321.
- Manish Prakash Gupta MP, Polena S, Coplan N, Panagopoulos G, Dhingra C, Myers J,Froelicher V.Prognostic Significance of Systolic Blood Pressure Increases in Men During Exercise Stress Testing. Am J Cardiol 2007;100:1609–1613.
- Aneja A, El-Atat F, McFarlane S. Hypertension and obesity, Sowers JR. Recent Prog Horm Res. 2004;59:169-205.
- Shibao C., Gamboa A, Diedrich A ve ark. Autonomic Contribution to blood pressure and metabolism in obesity. Hypertension 2007;49:27-33.
- Manabe H, Fukuma N, Tuchida T, Kato Y, Mabuchi K, Takano T. Analysis of alteration of blood pressure response to exercise through baroreflex. J Nippon Med Sch 2007;74:123-130.
- Walgenbach SC, Donald DE. Inhibition by carotid baroreflex by exercise induced increase in arterial pressure. Circ Res 1983;52:253-262.
- Melcher A, David ED. Maintained ability of carotid baroreflex to regulate arterial pressure during exercise. Am J Physiol 1981; 241:H838-H8499.
- Potts JT, Mitchell JH. Rapid resetting of carotid baroreceptor reflex by afferent input from muscle receptors. Am J Physiol 1998; 275:H2000-H2008.
- Ichinose M, Saito M, Kondo N, Nishiyasu T. Time- dependent modulation of arterial baroreflex control of muscle sympathetic nerve activity during isometric exercise in humans. Am J Physiol Heart Circ Physiol. 2006;290:H1419-H1426.
- Norton KH, Boushel S, Strange B, Saltin B, Raven PB. Resetting of the carotid arterial baroreflex during dynamic exercise in human. J Appl Physiol 1999;87:332-338.
- Kumagai S, Kai Y, Hanada H, Uezono K, Sasaki H. Relationships of the systolic blood pressure response during exercise with insulin resistance, obesity, and endurance fitness in men with type 2 diabetes mellitus.Metabolism. 2002;51(10):1247-52.
- Tsumura K, Hayashi T, Hamada C, Endo G, Fujii S, Okada K. Blood pressure response after two-step exercise as a powerful predictor of hypertension: the Osaka Health Survey.J Hypertens. 2002;20(8):1507-12.
- Miyatake N, Matsumoto S, Nishikawa H, Numata T. Relationship between body composition changes and the blood pressure response to exercise test in overweight Japanese subjects. Acta Med Okayama. 2007;61(1):1-7.
- Singh JP, Larson MG, Manolio T ve ark. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study.Circulation. 1999;99(14):1831-6.
- Di Bello V, Santini F, Di Cori A ve ark. Relationship between preclinical abnormalities of global and regional left ventricular function and insulin resistance in severe obesity: a Color Doppler Imaging Study. Int J Obes (Lond). 2006;30(6):948-56.
- Vriz O, Mos L, Frigo G ve ark.HARVEST Study Investigators. Effects of physical exercise on clinic and 24-hour ambulatory blood pressure in young subjects with mild hypertension. J Sports Med Phys Fitness. 2002 ;42(1):83-8.
- Brandon LJ, Elliott- Lloyd MB. Walking, body composition, and blood pressure dose-response in African American and white women. Ethn Dis. 2006 ;16(3):675-81.
- Hayashi T, Tsumura K, Suematsu C, Okada K, Fujii S, Endo G. Walking to work and the risk for hypertension in men: the Osaka Health Survey.Ann Intern Med. 1999;131(1):21-6.