___

• Akaneya, Y. (2007). The remarkable mechanism of prostaglandin E2 on synaptic plasticity. Gene Regul. Syst. Biol, 1, 83–89.
• Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., et al. (2011). Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci USA, 108:5003–8. doi: 10.1073/pnas.1019055108
• Aydın, H. (2005). Synopsis of Psychiatry, İstanbul, Güneş Kitabevi, 2: 134-153
• Babiarz, J. E., Ruby, J. G., Wang, Y., Bartel, D. P., (2008). Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev, 22:2773–2785.
• Bak, M., Silahtaroglu, A., Moller, M., et al. (2008). MicroRNA expression in the adult mouse central nervous system. RNA; 14, 432-444
• Bartel, D. P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 116(2), 281. doi: 10.1016/S0092-8674(04)00045-5.
• Bhat, S., Dao, D. T., Terrillion, C. E., Arad, M., Smith, R. J., Soldatov, N. M., Gould, T. D. (2012). CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease. Prog. Neurobiol. 99, 1–14.
• Breder, C. D., Dewitt, D., Kraig, R. P. (1995). Characterization of inducible cyclooxygenase in rat brain. J. Comp. Neurol. 355, 296–315
• Brzozka, M. M., Radyushkin, K., Wichert, S. P., Ehrenreich, H., Rossner, M. J. (2010). Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 in the brain. Biol. Psychiatry. 68, 33–40
• Cardo, L. F., Coto, E., Mena, L., Ribacoba, R., Moris, G., Menendez, M., Alvarez, V. (2013). Profile of microRNAs in the plasma of parkinson’s disease patients and healthy controls. J. Neurol. 260, 1420–1422. doi: 10.1007/s00415-013-6900-8.
• Dan-Dan Cao, Lu Li, and Wai-Yee Chan. (2016). MicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological Diseases. Int. J. Mol. Sci. 17(6), 842.doi: 10.33900/ijms17060842
• Davis, G. M., Haas, M. A., Pocock, R. (2015). MicroRNAs: Not “fine-tuners” but key regulators of neuronal development and function. Front. Neurol. 6, 245. doi: 10.3389/fneur.2015.00245. Denli, A. M., Tops, B. B., Plasterk, R. H., Ketting, R. F., Hannon, G. J. (2004). Nature. 432(7014), 231-5.
• Ebert, M. S., Neilson, J. R. ve Sharp, P. A. (2007). MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods, 4, 721–726.
• Emul, M., Kalelioğlu, T. (2015). Etiology of cardiovascular disease in patients with schizophrenia: current perspectives. Neuropsychiatr Dis Treat, 11, 2493-2503.
• Ertuğrul, A. (2010). Şizofreninin Nörobiyolojisi, Temel Psikofarmakoloji, Ankara, 1: 354,
• Gentner, B. et al. (2009). Stable knockdown of microRNA in vivo by lentiviral vectors. Nat. Methods 6, 63–66
• Girgenti, M. J., LoTurco, J. J., Maher, B. J. (2012). ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2. PLoS One, 7(2): e32404. https://doi.org/10.1371/journal.pone.0032404.
• Gotz, M., Huttner, W. B. (2005). The cell biology of neurogenesis. Nat. Rev. Mol. Cell Biol. 6, 777–788. doi: 10.1038/nrm1739.
• Guella, I., Sequeira, A., Rollins, B., Morgan, L., Torri, F., van Erp, TG., Myers, R. M., Barchas, J. D., Schatzberg, A. F., Watson, S. J., et al. (2013). Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. J. Psychiatr. Res. 47, 1215–1221.
• Han, J., Lee, Y., Yeom, K. H., Kim, Y. K., Jin, H., Kim, V. N., (2004). The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18(24), 3016-3027.
• Hansen, K. F., Karelina, K., Sakamoto, K., et al. (2013). MiRNA132: a dynamic regulator of cognitive capacity. Brain Struct Funct. 218, 817-831.
• Haqqani, A. S., Delaney, C. E., Tremblay, T. L., Sodja, C., Sandhu, J. K., Stanimirovic, D. B. (2013). Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells. Fluids Barriers CNS. 10(1), 4. doi: 10.1186/2045-8118-10-4.
• Hossain, S., Akaike, T., Chowdhury, E. H. (2010). Current approaches for drug delivery to central nervous system. Curr Drug Deliv. 7, 389‐397. Ipsaro, J. J., Joshua-Tor, L. (2015). From guide to target: molecular insights into eukaryotic RNA-interference machinery. Nat Struct Mol Biol. 22, 20–8. doi: 10.1038/nsmb.2931
• Junn, E., Mouradian, M. M. (2012). MicroRNAs in Neurodegenerative Diseases and Their Therapeutic Potential. Pharmacol Ther, 133, 142-150.
• Kaleb, M. Pauley, Seunghee, C., and Edward K. L. Chan. (2009). MicroRNA in autoimmunity and autoimmune diseases. J Autoimmun. 32(3-4), 189–194. doi:10.1016/j.jaut.2009.02.012
• Kaplan ve Sadock. (2005). Klinik Psikiyatri. Synopsis of Psychiatry Ninthedition.’den. Çeviri editörü: Hamdullah Aydın. 34-154, 2. baskı. Güneş kitabevi. İstanbul.
• Kasinski, A. L., Slack, F. J. (2012). Arresting the Culprit: Targeted Antagomir Delivery to Sequester Oncogenic miR-221 in HCC. Mol. Ther. Nucleic Acids. 1(3): e12.
• Kim, A. H., Parker, E. K., Williamson, V., McMichael, G. O. (2012). Fanous, A.H.; Vladimirov, V.I. Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137. Schizophr. Res, 141, 60–64
• Kluiver, J. et al. (2012). Rapid generation of microRNA sponges for microRNA inhibition. PloS One, 7(1): e29275.
• Krek, A., Grun, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., et al. (2005). Combinatorial microRNA target predictions. Nat Genet. 37(5), 495–500. doi: 10.1038/ng1536.
• Kunej, T., Godnic, I., Horvat, S., Zorc, M., Calin, G. A. (2012). Cross talk between microRNA and coding cancer genes. Cancer J. 18, 223–231
• Kwon, E., Wang, W., Tsai, L. H. (2013). Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. Mol Psychiatry. 18, 11–12.
• Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J. et al. (2003). The nuclear RNase III Drosha initiates mikroRNA processing. Nature 425(6956),415-9.
• Lee, Y., Jeon, K., Lee, J. T., Kim, S., Kim, V. N. (2002). MicroRNA maturation: stepwise processing and subcellular localization. European Molecular Biology Organization, 21, 4663-4670
• Lewis, B. P., Burge, C. B., Bartel, D. P. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 120(1), 15–20. doi: 10.1016/j.cell.2004.12.035.
• Liu, L., Yuan, G., Cheng, Z., Zhang, G., Liu, X., Zhang, H. (2013). Identification of the mRNA expression status of the dopamine d2 receptor and dopamine transporter in peripheral blood lymphocytes of schizophrenia patients. PLoS One. 8(9), e75259.
• Lund, E., Guttinger, S., Calado, A., Dahlberg, J. E., Kutay, U. (2004). Nuclear export of microRNA precursors. Science, 303(5654),95-8.
• Malmevik, J., Petri, R., Knauff, P., et al. (2016). Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs inhippocampal neurons. Scientific Reports, 6, 1-14.
• Mellios, N., et al. (2010). Gender-Specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia. Schizophr. Bull. 38(3),433-43.
• Messias, E. L., Chen, C., Eaton, W. W. (2007). Epidemiology of schizophrenia: review of findings and myths. Psychiatr Clin N Am. 30(3), 323–338. doi: 10.1016/j.psc.2007.04.007.
• Miller, B. H., Wahlestedt, C. (2010). MicroRNA dysregulation in psychiatric disease. Brain Res. 1338, 89–99. doi: 10.1016/j.brainres.2010.03.035.
• Miller, J. D., Ganat, Y. M., Kishinevsky, S., Bowman, R. L., Liu, B., Tu, E. Y., Mandal, P. K., Vera, E., Shim, J. W., Kriks, S., et al. (2013). Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell. 13, 691–705. doi: 10.1016/j.stem.2013.11.006.
• Mitchell, P. S., Parkin. R. K., Kroh, E. M., Fritz, B. R., Wyman, S. K., Pogosova-Agadjanyan E. L, et al. (2008). Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA. 105(30),10513-8. doi: 10.1073/pnas.0804549105
• Mondol, V., Pasquinelli, A. E. (2012). Let's make it happen: the role of let-7 microRNA in development. In Current topics in developmental biology: microRNAs in development (ed. Hornstein E), Academic Press, Waltham, MA. 1–30
• Narayan, A., Bommakanti, A., Patel, A. A. (2015). High-throughput RNA profiling via up-front sample parallelization. Nat. Methods. 12, 343–399. doi: 10.1038/nmeth.3311.
• Narry, K. V. (2005). Small RNAs: Classification, Biogenesis, and Function. Mol Cells, 19(1), 1-15
• Nowak, J. S., Michlewski, G. (2013). MiRNAs in development and pathogenesis of the nervous system. Biochem Soc Trans. 41(4), 815–820. doi: 10.1042/BST20130044.
• O'Brien, J., Hayder, H., Zayed, Y., Peng, C. (2018). Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation. Front Endocrinol (Lausanne). 3,9,402.
• Okada, C., Yamashita, E., Lee, SJ., Shibata, S., Katahira, J., Nakagawa, A., Yoneda, Y., Tsukihara, T., (2009). A high-resolution structure of the pre-microRNA nuclear export machinery. Science. 326(5957),1275-9.
• Okamura, K., Hagen, J. W., Duan, H., Tyler, D. M., Lai, E. C., (2007). The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell. 130:89–100
• Perkins, D. O., et al. (2007) microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol, 8(2), R27.
• Pitchiaya, S., Heinicke, L. A., Park, J. I., Cameron, E. L., Walter, N. G., (2017). Resolving subcellular miRNA trafficking and turnover at single-molecule resolution. Cell Rep. 19, 630–42. doi: 10.1016/j.celrep.2017.03.075
• Rajasethupathy, P., Fiumara, F., Sheridan, R., Betel, D., Puthanveettil, S. V., Russo, J. J., et al. (2009). Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticitythrough CREB. Neuron, 63, 803–817.
• Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., et al. (2017). An integrated expression atlas of miRNAs and their promoters in human and mouse. Nat Biotechnol. 35(9), 872-878. doi: 10.1038/nbt.3947.
• Roberts, T. C., and Wood, M. J. A., (2013). Therapeutic targeting of non-coding RNAs. Essays Biochem; (54), 127–145.
• Sang, N., Zhang, J., Marcheselli, V., Bazan, N. G., Chen, C., (2005). Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor. J. Neurosci. 25(43), 9858–9870. doi: 10.1523/JNEUROSCI.2392-05.2005
• Saydam, F., Değirmenci, İ., Güneş, H. V. (2011). Mikro RNA’lar ve kanser. Medical Journal, 38(1), 113-20.
• Schratt, G., (2011) microRNAs at the synapse. Nat. Rev. Neurosci. 12, 182. doi: 10.1038/nrn3010.
• Silber, J., Lim, D. A., Petritsch, C., Persson, A. I., Maunakea, A. K., Yu, M., Vandenberg, S. R., Ginzinger, D. G., James, C. D., Costello, J. F., et al. (2008). MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 6, 14. doi: 10.1186/1741-7015-6-14.
• Smalheiser, N. R., Lugli, G., (2009) microRNA regulation of synaptic plasticity. Neuromolecular Med, 11, 133–140.
• Smrt, R. D., et al. (2010) MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells, 28, 1060-1070
• Song, H., Sun, X., Zhang, L., Zhao, L., Guo, Z., Fan, H, et al. (2014) A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology ımprovement in schizophrenia patients before and after antipsychotic treatment. JPsychiatr Res, 54, 134–140
• Sun, E., Shi, Y. (2015). MicroRNAs: small molecules with big roles in neurodevelopment and diseases. Exp Neurol. 268, 46–53. doi: 10.1016/j.expneurol.2014.08.005.
• Sun, G., Ye, P., Murai, K., Lang, M.F., Li, S., Zhang, H., Li, W., Fu, C., Yin, J., Wang, A., et al. (2011). MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nat. Commun. 2, 529.
• Trang, P., Medina, PP., Wiggins, JF., et al. (2009). Regression of murine lung tumors by the let-7 microRNA. Oncogene. 29(11), 1580-7. doi: 10.1038/onc.2009.445.
• Van Spronsen, M., van Battum, E.Y., Kuijpers, M., Vangoor, V.R., Rietman, M.L., Pothof, J., Gumy, L.F., van IJcken, W.F.J., Akhmanova, A., Pasterkamp, R.J., et al. (2013). Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures. PLoS ONE. 8, e74907. doi: 10.1371/journal.pone.0074907
• Velagapudi, SP., Gallo, SM., Disney, MD., (2014). Sequence-based design of bioactive small molecules that target precursor microRNAs. Nature Chem. Biol.;10(4), 291–297.
• Viswanathan, G.Q., Daley, S.R., (2010) Lin28: a microRNA regulator with a macro role. Cell, 140, 445-449
• Wayman, GA., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, HYM., et al. (2008) An activity-regulated microRNA controls dendritic plasticity by down-regulatingp250GAP. Proc Natl Acad Sci U S A, 105, 9093–9098.
• Yang, JS., Maurin, T., Robine, N., Rasmussen, KD., Jeffrey, KL., Chandwani, R., Papapetrou, EP., Sadelain, M., O'Carroll, D., Lai, EC., (2010). Proc Natl Acad Sci ABD 107 (34): 15, 163-8.
• Yang, Y., Shu, X., Liu, D., et al. (2012). EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation. Neuron; 73, 774-788.
• Zhu, Y., et al. (2009) A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene Schizophr. Res, 1-4.