Klinik çalışmalarda örneklem genişliğinin belirlenmesine pratik yaklaşımlar

Örneklem genişliğinin belirlenmesi, klinik çalışmaların planlanmasında en önemli ve genellikle en zor basamaklardan birini oluşturur. Bu çalışmada, örneklem genişliğinin doğru bir şekilde belirlenebilmesi için bazı önemli noktalar üzerinde duruldu. Sonuçları güvenilir klinik çalışmalar tasarlanabilmesi için, bağımlı ve bağımsız iki örneklem t-testlerinde örneklem genişliğinin belirlenmesine ilişkin yol gösterici ipuçlarına değinilerek, pratik tablolar sunuldu.

Anahtar Kelimeler:

olgu çalışmaları, evcil hayvanlar, çiftlik hayvanları, sürü büyüklüğü, istatistiksel analizler

Practical approaches to the determination of the sample size in clinical studies

The problem of sample size determination is an important and generally difficult step of planning the statistical part of a clinical study. In this paper, some suggestions are made for determining the sample size in a successful and meaningful way. In order to design a high-quality clinical study with reliable results, practical tables and guiding clues are presented for sample size determination of t-tests for paired and independent samples.

Keywords:

case studies, domestic animals, livestock, livestock numbers, statistical analysis,

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