ÖZLEM GÜZEL, Esma YILDAR, Gamze KARABAĞLI, O. Dilek ERDIKMEN, Aslı EKİCİ

Comparison of the effects of spontaneous and mechanical ventilation on blood gases during general anaesthesia in dogs

Genel anestezide spontan ventilasyon, solunumun baskılanmasına ve atelektaziye yol açar. Mekanik ventilasyon tidal volümü artırır ve atelektaziyi giderir. Çalışma materyalini, farklı ırk, yaş ve cinsiyetteki toplam 20 köpek oluşturdu. Olgular, her grupta 10 köpek olacak şekilde 2ye ayrıldı. İlk grup spontan ventilasyon (SV), ikinci grup mekanik ventilasyon (MV) grubu olarak belirlendi. Anestezi indüksiyonunda her iki gruba, propofol 6 mg/kgdan intravenöz enjeksiyonla verildi. Tüm köpeklerden, propofol enjeksiyonunu takip eden 5. dakikada kan örnekleri alındı. Bu süre 0. dakika (T0) olarak değerlendirildi. Her iki grubun inhalasyon anestezisi izofloranla sürdürüldü. SV ve MV grubundaki olgulardan 15. dakika (T15), 30. dakika (T30) ve 60. dakika (T60)larda venöz kan örnekleri alındı. Kalp atım sayısı, solunum sayısı, SpO2, vücut ısısı ve kan gazları monitörize edildi. Çalışmanın istatistiki değerlendirmesi Tekrarlı Ölçüm Varyans Analizi metodu ile yapıldı. Elde edilen bulgular, incelenen parametreler yönünden SV ve MV grupları arasında istatistiki anlamda önemli bir fark olmadığını gösterdi. Ancak grup içi değerlendirmelerde, MV grubundaki köpeklerden elde edilen sonuçların, hastaların anestezi süresince stabil kalmaları açısından daha güvenilir olduğu sonucuna ulaşıldı.

Köpeklerde genel anestezi sürecinde spontan ve mekanik ventilasyonun kan gazları üzerine etkilerinin karşılaştırılması

Spontaneous ventilation during general anaesthesia leads to respiratory depression and atelectasis. Mechanical ventilation increases tidal volume and eliminates atelectasis. The study material consisted of a total of 20 dogs of different breed, age and gender. Dogs were divided into two groups, consisted of 10 dogs. The first group was established as the spontaneous ventilation (SV) group, while the second group was the mechanical ventilation (MV) group. For induction of anaesthesia, propofol was administered to both groups via intravenous injection at a dose of 6 mg/kg. Blood samples were collected from all dogs in 5 minutes after propofol administration. This period was determined as Minute 0 (T0). In both groups, inhalation anaesthesia was continued with isoflurane. Venous blood samples were collected from dogs in the SV and MV groups at 15 (T15), 30 (T30) and 60 (T60) minutes. Heart rate, respiratory rate, SpO2, body temperature and blood gases were monitored. Statistical evaluation of the study was carried out using the Repeated Measures Analysis of Variance method. The results obtained showed that there was no statistically significant difference between the SV and MV groups regarding the examined parameters. However, in the assessments within the group, results obtained from the dogs in the MV group were more reliable from the point of view of the patients remaining stable throughout anaesthesia.

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