AMAÇ: Bu çalıșmada RBPT ve/veya STAT testleri negatif olan klinik ve epidemiyolojik olarak bruselloz ile uyumlu hastalarda RBPT, STAT ve ELISA kombinasyonunun tanıdaki etkinliğinin değerlendirilmesi amaçlandı. YÖNTEM: Klinik ve epidemiyolojik olarak brusellozla uyumlu 66 olgunun serum örneği RBPT, STAT ve ELISA ile test edildi. RBT pozitif ve negatif kișilerde STAT ve/veya ELISA test sonuçları seropozitifl ik yö- nünden karșılaștırıldı. Veriler SPSS 16.0 bilgisayar programına girildi. Sonuçların istatistiksel analizi için Fischer Exact testi yapıldı. p

AIM: The aim of the study is to analyze the effi ciency of combination of RBPT, STAT and ELISA tests on patients with brucellosis where the diagnosis is dependent on the compatible clinical and epidemiological fi ndings with negative RBPT and/or STAT test results. METHODS: The serum samples of 66 patients having clinical and epidemiological fi ndings compatible with brucellosis were analyzed using the combination of RBPT, STAT and ELISA tests. Both positive and negative samples were re-analyzed for seropositivity by using the STAT or ELISA tests together. The results were statistically analyzed with the SPSS 16.0 computer program using the Fisher Exact test. The signifi cance level was defi ned as p< 0.05. RESULTS: Serum samples tested for brucellosis using the RBPT were found to be seropositive in 45.5% and seronegative in 54.5%. The seropositive group had a 73% seropositivity with the combination of STAT and ELISA tests. The seronegative group also had a 25% seropositivity with the combination of STAT and ELISA tests. Both groups’ seropositivity rate signifi cantly increased after the combination of the tests (p< 0.05). CONCLUSION: It seems that the combination of RBPT, STAT and ELISA tests increases the rate of seropositivity in patients with negative RBPT and /or STAT tests, particularly with a pre–diagnosis of brucellosis.