The purpose of this study is to study the satisfaction level of guest room safety management of resort hotels in Khao Kor District, Phetchabun Province. A researcher adopted a quantitative methodology used a questionnaire with the accidentally-met Thai 387 tourists travelling to Khao Kor District during winter season which is considered as a high season in the area.  The data from the questionnaire then is analyzed as descriptive statistics. Some interviews are conducted with the tourists to have more fruitful information.General information is analyzed by using descriptive statistics describing percentages.  Information on satisfactions of in-room safety management of hotels in Khao Kor District, Phetchabun Province is analyzed by using mean (X) and standard deviation (S.D.). The results revealed that the tourists are satisfied with the good condition and secured-lock guestroom door at most (X = 4.88), followed by the safe from outside danger of guestroom balcony (X = 4.84), the good condition and safe from danger of mosquito wire screens and curved steels (X = 4.74) respectively.  Although the least satisfaction of the tourists about in-room safety management is light and well-ventilated guestroom toilets and clean sanitary ware (X=4.05), it is still in high level.  Some useful suggestions from the tourists about the in-room safety management of hotels in Khao Kor District, Phetchabun Province are the hotels should have a safety instruction in English and Chinese version because it will be useful for international tourists in case of emergency, a floor plan and fire exit way should be clear both picture and wordings so it will be easy to evacuate safely.  In the meantime, next researcher should conduct other kinds of hotels in Khao Kor District such as guesthouses that are quite popular among the tourists to be aware of safety management may have.