Şahin ŞAHİNALP, Kadir ÇEVİKER, M.f.tolga SOYAL, Ali GÜR

Erişkin hastalarda kardiyopulmoner baypas ile uygulanan konvansiyonel ultrafiltrasyonun nötrofil / lenfosit oranı ile retrospektif olarak değerlendirilmesi

Amaç: Bu çalışmanın amacı, nötrofil / lenfosit oranını (NLO) değerlendirerek, kardiyopulmoner baypas (CPB) ile açık kalp cerrahisi geçiren yetişkin hastalarda ultrafiltrasyonun (UF) etkinliğini araştırmaktır. Yöntemler: Ocak 2016'dan Aralık 2018'e kadar bir Üniversite hastanesinde CPB uygulanan 288 yetişkin hasta üzerinde retrospektif bir kohort çalışması yapılmıştır. Nötrofil, lenfosit ve trombosit sayısı, BUN, kreatinin ve C-reaktif protein (CRP) dahil olmak üzere tüm perioperatif klinik veriler geriye dönük olarak toplandı. UF'nin etkinliği ve NLO, nötrofil, lenfosit ve trombosit sayısı, postoperatif kanama, ekstübasyon süresi, yoğun bakım ünitesinde (YBÜ) kalış süresi ve hastanede kalış süresi ile ilişkisi analiz edildi. Bulgular: Nötrofil sayısı, NLO ve CRP ameliyat öncesi değerlere göre ameliyat sonrası anlamlı olarak arttı (P

Anahtar Kelimeler:

Erişkin hasta, Kardiyo-pulmoner baypas, Ultrafiltrasyon, Nötrofil lenfosit oranı, Trombosit, Enflamasyon

Retrospective evaluation of ultrafiltration during cardiac surgery with cardiopulmonary bypass in adult patients with increased neutrophil to lymphocyte ratio

Aim: The aim of this study was to investigate the efficacy of the ultrafiltration (UF) in adult patients undergoing open-heart surgery with cardiopulmonary bypass (CPB) by evaluating the neutrophil to lymphocyte ratio (NLR). Methods: A retrospective case-control study was conducted on 288 adult patients who underwent CPB in a University hospital from January 2016 to December 2018. The study groups were composed of a control group (n=116) of patients who underwent surgery without UF and the study group (n=172) of patients who underwent surgery with UF. All perioperative clinical data, including neutrophil, lymphocyte and platelet count, BUN, creatinine, and C-reactive protein (CRP) values were collected. The efficacy of UF and its association with NLR, neutrophil, lymphocyte and platelet count, postoperative bleeding, extubation time, duration of intensive care unit (ICU) stay and in-hospital stay were analyzed. Results: Neutrophil count, NLR and CRP significantly increased post-operatively compared to pre-operative values (P

Keywords:

adult patients, cardiopulmonary bypass, ultrafiltration, neutrophil lymphocyte ratio, platelet, inflammation,

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