The Utilization Areas of Cabergoline in Veterinary Gynecology
Cabergoline is a potent dopamine agonist and a synthetic ergot derivative, and it acts by inhibiting prolactin secretion from the pituitary
___
- 1- Colao A, Di Sarno A, Sarnacchiaro F, et al. Prolactinomas
resistant to standard dopamine agonists respond
to chronic cabergoline treatment. Int J Clin Endocrinol
Metab. 1997; 82(3): 876-883.
- 2- Kaya S. Üremeyi Etkileyen Hormonlar
In: Kaya S, ed. Veteriner Farmakoloji
4. Baskı Ankara Medisan Yayınevi 2007:81
- 3- Balçık O, 2007. Hiperprolaktinomide kabergolinin
düşük doz ve kısa dönem idame tedavisinin etkinliğinin
araştırılması. T.C. Saglık Bakanlıgı Dr. Lütfi
Kırdar Kartal Egitim ve Arastırma Hastanesi 2. Kadın
Hastalıkları ve Dogum Klinigi Uzmanlık Tezi
- 4- Colao A, Di Sarno A, Landi ML, et al. Macroprolactinoma
shrinkage during cabergoline treatment is greater
in naive patients than in patients pretreated with other
dopamine agonists: a prospective study in 110 patients.
Int J Clin Endocrinol Metab. 2000; 85(6):2247-2252.
- 5- Jochle W, Arbeiter K, Post K, Ballabio R. Effects on
pseudo-pregnancy, pregnancy and interoestrous intervals
of pharmacological suppression of prolactin secretion
in female dogs and cats. J Reprod Fertil. 1989;
39:199-207
- 6- Verstegen JP, Onclin K, Silva LD, et al. Abortion induction
in the cat using prostaglandin F2 alpha and a new
anti-prolactinic agent, cabergoline. J Reprod Fertil.
1993; ( 47): 411-417.
- 7- Eguchi K, Kawamoto K, Uozumi T, et al. Effect of Cabergoline,
a Dopamine Agonist, on Estrogen-Induced
Rat Pituitary Tumors. Endocr J. 1995; 42(3): 413-420.
- 8- Concannon PW. Reproductive cycles of the domestic
bitch. Anim Reprod Sci. 2011; 124(3): 200-210.
- 9- Nak D, Nak Y, Simsek G. Comparison of the use of cabergoline
and gonadotrophin to treat primary and secondary
anoestrus in bitches. Aust Vet J. 2012; 90(5): 194-
196.
- 10- Kalkan C, Horoz H, 2001. Pubertas ve Seksüel Sikluslar
In: Alaçam E, ed. Evcil Hayvanlarda Doğum ve İnfertilite
3. Baskı Ankara Medisan Yayınevi 2001: 23-40
11- Rains CP, Bryson HM, Fitton A. Cabergoline. Drugs.
1995; 49(2): 255-279.
- 12- Günay A, 2015. Köpeklerde Östrus Siklusunu Uyarma
Yöntemleri. Acta Vet Eurasia. 2015; 41(2): 238-244.
13- Kutzler MA. Estrus induction and synchronization in
canids and felids. Theriogenology. 2007; 68(3):354-
374.
- 14- Gobello C, Castex G, Corrada Y. Use of cabergoline
to treat primary and secondary anestrus in dogs. JAVMA.
2002; 220(11): 1653-1654.
- 15- Verstegen JP, Onclin K, Silva LDM, et al. Effect of stage
of anestrus on the induction of estrus by the dopamine
agonist cabergoline in dogs. Theriogenology. 1999;
51(3): 597-611.
- 16- Rota A, Mollo A, Marinelli L, et al. Evaluation of cabergoline
and buserelin efficacy for oestrous induction in
the bitch. Reprod Domest Anim. 2003; 38(6): 440-443.
- 17- Cirit U, Bacınoglu, S, Tas M, et al. Use of a decreased
dose of cabergoline to treat secondary anoestrus in
bitches. Bull Vet Inst Pulawy. 2007; 51(1):43-46.
- 18- Gobello C. Dopamine agonists, anti-progestins, anti-
androgens, long-term-release GnRH agonists and
anti-estrogens in canine reproduction. Theriogenology.
2006; 66(6): 1560-1567.
- 19- Wanke MM, Romagnoli S, Verstegen J, Concannon
PW. Pharmacological approaches to pregnancy termination
in dogs and cats including the use of prostaglandins,
dopamine agonists, and dexamethasone
In: Concannon PW, England G, Verstegen J and C.
Linde-Forsberg , ed.Recent Advances in Small Animal
Reproduction, Publisher: International Veterinary Information
Service (www.ivis.org), Ithaca, New York,
USA.. This document is available on-line at www.ivis.
org. 2002; Document No. A1223.0802.
- 20- Post K, Evans LE, Jöchle W. Effects of prolactin suppression
with cabergoline on the pregnancy of the
bitch. Theriogenology. 1998; 29(6): 1233-1243.
- 21- Onclin K, Silva LD, Donnay I, et al. Luteotrophic action
of prolactin in dogs and the effects of a dopamine agonist,
cabergoline. J Reprod Infertil. 1992; (47):403-409.
- 22- Arbeiter K, Flatscher C. Induction of abortion in the
bitch using cabergoline (Galastop). Kleintierpraxis.
1996; 41: 747.
- 23- Eilts BE. Pregnancy termination in the bitch and
queen. Top Companion Anim Med. 2002; 17(3): 116-
123.
- 24- Wiebe, VJ, Howard, JP. Pharmacologic advances in canine
and feline reproduction. Top Companion Anim
Med. 2009; 24(2): 71-99.
- 25- Erünal-Maral N, Aslan S, Fındık M, et al. Alfaprostol
(Gabbrostim™) induction of abortion in queens by administration
of cabergoline (Galastop™) solely or in
combination with the PGF2α analogue. Theriogenology.
2004; 61(7): 1471-1475.
- 26- Hollinshead F, Krekeler N. Pyometra in the queen: To
spay or not to spay? J Feline Med Surg. 2016; 18(1):
21-33.
- 27- England GCW, Freeman SL, Russo M. Treatment of
spontaneous pyometra in 22 bitches with a combination
of cabergoline and cloprostenol. Vet Rec. 2007;
160: 293-296.
- 28- Jena B, Rao KS, Reddy KCS, et al. Comparative efficacy
of various therapeutic protocols in the treatment of
pyometra in bitches. Vet Med. 2013; 58(5): 271-276.
- 29- Gobello C, De La Sota RL, Goya RG. A review of canine
pseudocyesis. Reprod Domest Anim. 2001; 36(6):
283-288.
- 30- Tsutsui T, Kirihara N, Hori T, et al. Plasma progesterone
and prolactin concentrations in overtly pseudopregnant
bitches: a clinical study. Theriogenology. 2007; 67(5):
1032-1038.
- 31- Mir F, Fontfaonne A. Management of pseudopregnancy
lactation refractory to medical treatment in bitches
Point Veterinaire. 2013; 44(334): 6-9.
- 32- Giesenberg S. Pseudopregnancy in the bitch. Aust Vet
P. 2004; 34(4): 164-168.
- 33- Harvey MJA, Cauvin A, Dale M, et al. Effect and mechanisms
of the antiprolactin drug cabergoline on pseudopregnancy
in the bitch. J Small Anim Pract. 1997;
38(8):36-339.
- 34- Baştan A, Fındık M, Erunal N, et al. The use of cabergoline for treatment of pseudopregnancy
in dogs with the purpose of suppressing lactation.
Reprod Domest Anim. 1998; 33(2): 49-53.
- 35- Sathiamoorthy T, Kulasekar K, Joseph C, et al. Clinical
management of pseudopregnancy in bitches
with cabergoline. Indian Vet J. 2007; 84(2): 184-
185.
- 36- Dvojkovic N, Macesic N, Bacic G, et al. Feline fibroepithelial
hyperplasia (FEH) treatment options. Kleintierpraxis.
2015; 60(5): 237-243.
- 37- Wehrend A, Hospes R, Gruber AD. Treatment of feline
mammary fibroadenomatous hyperplasia with a
progesterone-antagonist. Vet Rec. 2001; 148(11): 346.
- 38- MacDougalL LD. Mammary fibroadenomatous hyperplasia
in a young cat attributed to treatment with
megestrol acetate. Can Vet J. 2003; 44(3): 227-229.
- 39- Concannon PW, Verstegen J. Some unique aspects of
canine and feline female reproduction important in
veterinary practice. In Proc.: 3rd World Congress of
the World Small Anim. Vet. Assoc. 11-14 May 2005.
Mexico City, Mexico.
- 40- Uçmak M, Enginler SÖ, Gündüz MC, et al. Treatment
of Feline Mammary Fibroepithelial Hyperplasia with
the Combination of Aglepristone and Cabergoline.
Acta Vet Eurasia. 2011; 37(1): 69-74.
- 41- Boutinaud M, Isaka N., Lollivier V, et al. Cabergoline
inhibits prolactin secretion and accelerates involution
in dairy cows after dry-off. J Dairy Sci. 2016; 99(7):
5707-5718.
- 42- Özyurtlu N, Doğruer G, 2016. Memenin Fizyolojisi In:
Kaymaz M. , Fındık M. , Rişvanlı A. , Köker A, ed.Evcil
Hayvanlarda Meme Hastalıkları 1. Baskı Malatya
Medipres Matbaacılık Yayıncılık Ltd. Şti. 2016: 23-35.
- 43- Bach A, De-Prado A, Aris A. The effects of cabergoline
administration at dry-off of lactating cows on udder
engorgement, milk leakages, and lying behavior. J
Dairy Sci. 2015; 98(10): 7097-7101.
- 44- Bertulat S, Isaka N, de Prado A, et al. Effect of a single
injection of cabergoline at dry off on udder characteristics
in high-yielding dairy cows. J Dairy Sci. 2017;
100(4): 3220-3232.