Recent advances in iron catalyzed reactions in organic synthesis
Recent advances in iron catalyzed reactions in organic synthesis
The transition metal catalyzed reactions are widely developed in current years. Most of the transition metals are expensive and are not easily available like; Gold (Au), Iridium (Ir), Palladium (Pd), Platinum (Pt), Ruthenium (Ru), Rhodium (Rh) etc. Iron is one of the highly plentiful, cheap and easily available transition metals. It has been consistently used in organic synthesis nowadays. In this review we have described the role of iron in organic reactions like C-C, C-O, C-N, C-S and N-S bond forming reactions. This review highlights the advancements in iron based organocatalysis from 2005 to 2020.
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- Andersen, N. G., & Keay, B. A. 2-Furyl phosphines as ligands for transition-metal-mediated organic synthesis. Chemical Reviews 2001; 101 (4): 997-1030.
- Collman J. P., Hegedus, L. S., Norton, J. R., Finke, R. G. Principles and applications of organotransition metal chemistry; University Science Book: Mill Valley, CA,
1987.
- Roughley, S. D., & Jordan, A. M. The medicinal chemist’s toolbox: an analysis of reactions used in the pursuit of drug candidates. Journal of Medicinal Chemistry 2011; 54 (10): 3451–3479. doi:10.1021/jm200187y
- Garrett, C. E., & Prasad, K. The art of meeting palladium specifications in active pharmaceutical ingredients produced by pd-catalyzed reactions. Advanced Synthesis & Catalysis 2004; 346(8): 8 8 9 – 9 0 0 . doi:1 0.1002/adsc.200404071