Tünay Karan, Saban TEKIN, Ahmet BURSALI, Adem KESKIN

Investigation of Tick-Borne Encephalitis Virus (TBEV) in Ixodid Ticks Collected from Central Black Sea Region in Turkey

–Tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus causes thousands of Tick-borne encephalitis (TBE) cases annually throughout Europe. TBE is an infectious disease involving the central nervous system, which may result in death. TBEV is transmitted to humans by ixodid tick species such as Ixodes ricinus, Ixodes persulcatus and Haemaphysalis concinna. To date, there is no evidence for the presence of TBEV in Turkish ticks. In the present study, presence of TBEV in Ixodid ticks collected from humans in Amasya, Tokat and Ordu provinces was investigated using Revers Transcriptase Polimerase Chain Reaction (RT-PCR). A total 918 tick specimens were collected from humans applying health centers with tick bites in Amasya (n=630), Tokat (n=60) and Ordu (n=228), provinces located in Central Black Sea Region. According to RT-PCR results, no TBEV detected in Ixodes ricinus or other ixodid tick species tested in this study. This result indicates that the tick species tested from the region have no potential for transmission of TBEV

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T.P. Monath, In The Togaviridae and Flaviviridae, eds. Schlesinger, S.& Schlesinger, M. J. (Plenum, New York), (1986) pp. 375-440.
D. Hayasaka, L. Ivanov, G.N. Leonova, A. Goto, K. Yoshii, T. Mizutani, Distribution and characterization of tick-borne encephalitis viruses from Siberia and far-eastern Asia. J. Gen. Virol. (2001) 82: 1319–28.
I. Golovljova, S. Vene, K.B. Sjolander, V. Vasilenko, A. P lyusnin, A. Lundkvist, Characterization of tick-borne encephalitis virus from Estonia. J. Med. Virol. (2004) 74: 580–8.
T.G. Jaenson, L.Talleklint, L. Lundqvist, B. Olsen, J. Chirico, H. Mejlon, distribution, host associations, and vector roles of ticks (Acari: Ixodidae, Argasidae) in Sweden. J. Med. Entomol. (1994) 31: 240–56.
S. Randolph, Evidence that climate change has caused “emergence” of tick-borne in Europe. J. Med. Microbiol. (2004) 293: 5–15.
J. Süss, C. Klaus, R. Diller, C. Schrader,N. Wohanka, U. Abel,TBE incidence versus virus prevalence and increased prevalence of the TBE in Ixodes ricinius removed from humans. International Journal of Medical Microbiology. (2006) 296: 63-68.
C. Brinkley, P. Nolskog, I. Golovljova, Tick-borne encephalitis virus natural foci emerge in Western Sweden. Int J. Med Microbiol. (2008) 298: 73-80.
M. Weidmann, P., Schmidt, F.T. Hufert, K. Krivanec, H. Meyer, Tick-Borne Encephalitis Virus in Clethrionomys glareolus in the Czech Republic.Vector-Borne And Zoonotic Diseases. (2006) 6: 379-381.
P. D’Agaro, E. Martinelli, P. Burgnich, F. Nazzi, S. Del Fabbro, A. Iob, M., Ruscio, P. Pischiutti, C.Campello, Prevalence of tick-borne encephalitis virus in Ixodes ricinus from a novel endemic area of North Eastern Italy. J. Med. Virol. (2009) 81: 309–316.
A.,Wójcik-Fatlaa, E. Cisaka,V. Zajaca, J Zwolinski, J. Dutkiewicza, Prevalence of tick-borne encephalitis virus in Ixodes ricinus and Dermacentor reticulatus ticks collected from the Lublin region (eastern Poland). Ticks and Tick-borne Diseases, (2011) 2: 16–19.
T.Takeda, T. Ito, M. Osada, K. Takahashi, I. Takashima, Isolation of tick- born encephalitis virus from wild rodents and a seroepizootiologic survey in Hokkaido, Japan. Am. J. Trop. Hyg. (1999) 60: 287–291.
B. Esen, A. Gozalan, N. Coplu, F.S Tapar, R. Uzun, T. Aslan, M. Ertek, T. Buzgan, L. Akin, The presence of tick-borne encephalitis in an endemic area for tick-borne diseases, Turkey. Trop Doct. (2008) 38: 27-8.
K. Ergunay, N. Ozer, D. Us, A. Ozkul, F. Simsek, S. Kaynas, S. Ustacelebi, Seroprevalence of West Nile virus and tick-borne encephalitis virus in southeastern Turkey: first evidence tick-borne encephalitis virus infections.Vector Borne Zoonotic Dis. (2007) 7: 157-61.
H. Albayrak, E. Ozan, M. Kurt, Molecular Detection of Crimean-Congo Hemorrhagic Fever Virus (CCHFV) but not West Nile Virus (WNV) in Hard Ticks from Provinces in Northern Turkey, Zoonoses Public Health. (2010) 57: 156–160.
B.I. Pomerantzev, Ixodid ticks (Ixodidae). Fauna SSSR. Paukoo-braznye (1950) 4:224 (In Russian).
N.A. Filippova, Ixodid Ticks of Subfamily Amblyomminae Fauna of Russia and Neighboring Countries. 1997 4(5). Nauka Publishing House, St. Petersburg, 436 pp.
D.A Apanaskevich, I.G. Horak, The Genus Hyalomma Koch, 1844. V. Reevaluation of the taxonomic rank of taxa comprising the H. (Euhyalomma) marginatum koch complex species (Acari: Ixodidae) with redescription of all parasitic stages and on biology, Int. J. Acarol. (2008) 34: 13–42.
A. Bursali, A. Keskin, S. Tekin. A review of the ticks (Acari: Ixodida) of Turkey: species diversity, hosts and geographical distribution. Experimental and Applied Acarology, (2012), 57(1): 91-104.
A. Keskin, T.K., Koprulu, A., Bursali, A.C., Ozsemir, K.E., Yavuz, S., Tekin. First Record of Ixodes arboricola (Ixodida: Ixodidae) From Turkey With Presence of Candidatus Rickettsia vini (Rickettsiales: Rickettsiaceae). J. Med. Entomol. (2014) 51(4): 864-867.
A. Bursali, S.Tekin, A. Keskin, M. Ekici, E. Dundar, Species diversity of ixodid ticks feeding on humans in Amasya,Turkey. Seasonal abundance and presence of Crimean- Congo hemorrhagic fever virus. J. Med. Entomol. (2011) 48: 85–93.
S. Tekin, A., Bursali, N., Mutluay, A. Keskin, E. Dundar. Crimean-Congo Hemorrhagic Fever Virus in various ixodid tick species from a highly endemic area. Veterinary Parasitology, (2012) 186(3): 546-552.
Y. Uyar, I. Christova, A. Papa, Current situation of Crimean Congo Hemorrhagic fever (CCHF) in Anatolia and Balkan Peninsula. Turk. Hij. Den. Biyol.Derg. (2011) 68: 139-51.
E.S. Guner, N. Hashimoto, N. Takada, K. Kaneda, Y. Imai and T. Masuzawa, First isolation and characterization of Borrelia burgdorferi sensu lato strains from Ixodes ricinus ticks in Turkey. J. Med. Microbiol. (2003) 52: 807–813.
K. Ergunay, M.B. Saygan, S. Aydoğan, N. Litzba, B. Sener, S. Lederer, M. Niedrig, G. Hasçelik, D.Us, Confirmed exposure to tick-borne encephalitis virus and probable Human cases of tick-borne encephalitis in Central/Northern Anatolia, Turkey. Zoonoses Public Health. (2011) 58: 220-7.
W. Melik, A.S. Nilsson, and M. Johansson, Detection strategies of tick-borne encephalitis virus in Swedish Ixodes ricinius reveal evolutionary characteristics of emerging tick-borne flaviviruses. Archies of Virology. (2007) 152: 1027-1034.

ISSN: 1304-7981
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 2012
Yayıncı: Tokat Gaziosmanpaşa Üniversitesi

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