Guliz SENORMANCİ, Osman Hasan Tahsin KİLİC, Omer SENORMANCİ

A case of spontaneous ejaculation associated with panic disorder which was treated with sertraline and alprazolam

Anxiety may coincide with sexual arousal. Same sympathetic and parasympathetic pathways involving in both conditions may be responsible for this coincidence and anxiety and sexual arousal have similar physiological features. In this case report, we present a 20 year old male patient experiencing spontaneous ejaculations that occur without a prior sexual arousal, and without erection during panic attacks. The ejaculations were not reported to be pleasurable and the content of though included thoughts of guilt due to spontaneous ejaculations. The patient recovered from both panic attacks and spontaneous ejaculation after receiving pharmacological treatment.

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1. Redmond DE Jr, Kosten TR, Reiser MF. Spontaneous ejaculation associated with anxiety: Psychophysiological considerations. Am J Psychiatry. 1983;140(9):1163-6. [CrossRef]
2. Figueira I, Possidente E, Marques C, Hayes K. Sexual dysfunction: a neglected complication of panic disorder and social phobia. Arch Sex Behav. 2001;30(4):369-77. [CrossRef]
3. Freeman SA. Panic attacks with spontaneous ejaculation successfully treated with citalopram and clonazepam. J Clin Psychopharmacol. 2004;24(4):463-4. [CrossRef]
4. Bandelow B. Assessing the efficacy of treatments for panic disorder and agoraphobia. II. The Panic and Agoraphobia Scale. Int Clin Psychopharmacol. 1995;10(2):73-81. [CrossRef]
5. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32(1):50-5. [CrossRef]
6. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol. 1967;6(4):278-96. [CrossRef]
7. Hallward A, Ellison JM. The physiology of sexual function. In Antidepressants and sexual function. London: Harcourt Health Communications. 2001:8-27.
8. Waldinger MD. The neurobiological approach to premature ejaculation. J Urol. 2002;168(6):2359-67. [CrossRef]
9. Kaplan SA. Side Effects of alpha-blocker use: Retrograde ejaculation. Rev Urol. 2009;11(Suppl 1):S14-S8.
10. Wilkinson DJ, Thompson JM, Lambert GW, Jennings GL, Schwarz RG, Jefferys D, et al. Sympathetic activity in patients with panic disorder at rest, under laboratory mental stress, and during panic attacks. Arch Gen Psychiatry. 1998;55(6):511-20. [CrossRef]
11. Cameron OG, Smith CB, Nesse RM, Hill EM, Hollingsworth PJ, Abelson JA, et al. Platelet alpha 2-adrenoreceptors, catecholamines, hemodynamic variables, and anxiety in panic patients and their asymptomatic relatives. Psychosom Med. 1996;58(4):289-301. [CrossRef]
12. Waldinger MD, Berendsen HH, Blok BF, Olivier B, Holstege G. Premature ejaculation and serotonergic antidepressants-induced delayed ejaculation: the involvement of the serotonergic system. Behav Brain Res. 1998;92(2):111-8. [CrossRef]