After more than one year, the Novel Corona Virus (COVID-19) pandemic is still going on. In this retrospective study, we reported clinical characteristics of patients who died cause of COVID-19. A total of 32 (7.6%) deaths were recorded among 422 patients with COVID-19, of which 280 (66.3%) patients were male and 142 (33.7%) female. Males had a significantly higher death incidence than females (26/32, 81.25% vs. 6/32, 18.75%, respectively; P-value >0.001). Hypertension (14; 43.8%) and Diabetes Mellitus (13; 40.6%) were the most common independent comorbidities among patients. Other risk factors are heart disease, renal disease, chemotherapy, and corticosteroid therapy. Dyspnea and cough were the most frequent symptom of admission. Increased levels of ESR and creatinine are significantly associated with mortality. J Microbiol Infect Dis 2021; 11(4):239-241.