A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia

A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia

Objectives: Infections in infants<90 days old are the leading cause of morbidity and hospitalization in neonatal practice. The etiological agents of sepsis (with or without meningitis) in Saudi neonates <90 days old are vastly under-characterized. The aim of this study was to determine the bacterial etiology of neonatal sepsis and meningitis in these infants. Materials and methods: This retrospective study was conducted in King Khalid University Hospital, Riyadh, in the period from January 2007 to January 2011. All infants<90 days old with suspected sepsis during this period were examined for evidence of infection. Cultures, including blood and Cerebrospinal fluid (CSF) were performed for all neonates. Results: A total of 304 cases of sepsis in infants <90 days were investigated. Community-acquired neonatal sepsis composed 284 of the studied cases present after the age of one month, while 20 infants were identified as having neonatal sepsis in the first month of life. Only 12 blood cultures were positive (four isolates of Staphylococcus epidermidis, two Staphylococcus aureus, two Staphylococcus hominis, one Enterobacter cloacae, one group B streptococcus, one diphtheroids and one with Bacillus species). Only three cases yielded positive CSF cultures. The first of these was positive for Aeromonas hydrophila, the second for Clostridium tertium and the third for Escherichia coli. Conclusion: Suspected sepsis in infants <90 days old is relatively common in this hospital, with 304 cases in a four-year period. However, positive bacterial cultures were rare, constituting only 5% of the suspected cases.

Kaynakça

Sundaram V, Kumar P, Dutta S. Blood culture confirmed bac- terial sepsis in neonates in a North Indian tertiary care cen- ter: changes over the last decade. Jpn J Infect Dis 2009; 62:46-50.

Sankar MJ, Agarwal R, Jeevasankar M. Sepsis in the new- born. Indian J Pediat 2008; 75:261-272.

Darmstadt G, Batra M, Zaidi A. Parental antibiotics for the treatment of serious neonatal bacterial infections in devel- oping country communities. Pediatric infect Dis J 2009; 28: S37 – S42.

Zhu ML, Zheng G, Chen JN, Lin ZL, Zhu JH, Lin J. Compara- tive analysis of the pathogens responsible for hospital ac- quired and community acquired late onset neonatal septice- mia. Zhonghua Er Ke Za Zhi 2008; 46: 124-127.

Mokuolu AO, Jiya N, Adesiyun OO. Neonatal septicaemia in Ilorin: bacterial pathogens and antibiotic sensitivity pattern. Afr J Med Sci 2002; 31:127-130.

Zaidi A, Thaver D, Alos, Khan A. Pathogens Associated with sepsis in Newborns and young infants in Developing coun- tries. Pediatric Infect Dis J 2009; 28 S10-S18.

Gatchalian S, Quiambao B, Morelos A. Bacterial and viral etiology of serious infections in very young Filipino infants. Pediatric Infect Dis J 1999; 18:50-55.

Viswanathan R, Singh AK, Mukherjee S, Mukherjee, Das P, Basu S. Aetiology and Antimicrobial Resistance of Neonatal Sepsis at a Tertiary Care Centre in Eastern India: A 3 Year Study. Indian J Pediatr 2010; 17:300-304.

Baraff LJ. Management of infants and young children with fe- ver without source. Pediatr Ann 2008; 37:673-679.

Zaidi AKM, Huskins WC, Thaver,D, et al.: Hospital ac- quired neonatal infections in developing countries. Lancet 2005;365:1175-1188.

Osrin D, Vernanos, Costello A. Serious bacterial infections in newborn infants in developing countries. Curr Opin Infect Dis 2004; 17:217-24.

Ben Humida NE, Harouni M, Chaonachis Sfar R, Marrakchi Z. Early onset neonatal bacterial infections: A series of 144 cases. Tunis Med 2008; 86:136-139.

Nandyal RR. Update on group B streptococcal infections: perinatal and neonatal periods. J Perinat Neonatal Nurs 2008; 22:230-237.

Chirico G, Cortinouis S, Fonte C, Giudicig Bacterial sepsis. J Chemotherapy 2007; 19:S28-30.

Arnon S, Litmanovitz I. Diagnostic tests in neonatal sepsis. Curr Opin Infect Dis 2008; 21: 223-227.

Thaver D, Zaidi A. Burden of Neonatal Infections in develop- ing countries: A Review of Evidence from Community Based Studies, Pediatric infect Dis J 2009;28: S3-S9.

Kaynak Göster

Bibtex @ { jmid123179, journal = {Journal of Microbiology and Infectious Diseases}, issn = {2146-3158}, eissn = {2146-9369}, address = {}, publisher = {Sağlık Araştırmaları Derneği}, year = {2011}, volume = {1}, pages = {47 - 52}, doi = {10.5799/jmid.123179}, title = {A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia}, key = {cite}, author = {Bukhari, Elham Essa and Alrabiaah, Abdulkarim Abdullah} }
APA Bukhari, E , Alrabiaah, A . (2011). A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia . Journal of Microbiology and Infectious Diseases , 1 (02) , 47-52 . DOI: 10.5799/jmid.123179
MLA Bukhari, E , Alrabiaah, A . "A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia" . Journal of Microbiology and Infectious Diseases 1 (2011 ): 47-52 <
Chicago Bukhari, E , Alrabiaah, A . "A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia". Journal of Microbiology and Infectious Diseases 1 (2011 ): 47-52
RIS TY - JOUR T1 - A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia AU - Elham Essa Bukhari , Abdulkarim Abdullah Alrabiaah Y1 - 2011 PY - 2011 N1 - doi: 10.5799/jmid.123179 DO - 10.5799/jmid.123179 T2 - Journal of Microbiology and Infectious Diseases JF - Journal JO - JOR SP - 47 EP - 52 VL - 1 IS - 02 SN - 2146-3158-2146-9369 M3 - doi: 10.5799/jmid.123179 UR - Y2 - 2021 ER -
EndNote %0 Journal of Microbiology and Infectious Diseases A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia %A Elham Essa Bukhari , Abdulkarim Abdullah Alrabiaah %T A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia %D 2011 %J Journal of Microbiology and Infectious Diseases %P 2146-3158-2146-9369 %V 1 %N 02 %R doi: 10.5799/jmid.123179 %U 10.5799/jmid.123179
ISNAD Bukhari, Elham Essa , Alrabiaah, Abdulkarim Abdullah . "A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia". Journal of Microbiology and Infectious Diseases 1 / 02 (Haziran 2011): 47-52 .
AMA Bukhari E , Alrabiaah A . A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia. J Microbil Infect Dis. 2011; 1(02): 47-52.
Vancouver Bukhari E , Alrabiaah A . A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia. Journal of Microbiology and Infectious Diseases. 2011; 1(02): 47-52.
IEEE E. Bukhari ve A. Alrabiaah , "A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia", Journal of Microbiology and Infectious Diseases, c. 1, sayı. 02, ss. 47-52, Haz. 2011, doi:10.5799/jmid.123179
  • ISSN: 2146-3158
  • Yayın Aralığı: Yılda 4 Sayı
  • Yayıncı: Sağlık Araştırmaları Derneği

17.4b 12.3b

Sayıdaki Diğer Makaleler

Diagnosis of pertussis in vaccinated children of Khairpur, Sindh, Pakistan by Cough Plate Method

Amjad Ali Mughal, Yasmeen Faiz Kazi, Syed Habib Bukhari

Comparison of lamivudine - α-interferon combination and α-interferon

Mustafa Kemal Çelen, Celal Ayaz, Habibe Çolak, Recep Tekin

Attitudes and behaviors of Family Physicians regarding use of antibiotics

Oğuz Karabay, Davut Özdemir, Ertuğrul Güçlü, Mustafa Yıldırım, Nevin İnce, Abdulkadir Küçükbayrak, Selma Çakır, Mustafa Gülenç, Mehmet İnce, Keziban Demirli

A case with chronic hepatitis B and anterior uveitis - Is there any connection?

Şükran Köse, Süheyla Serin Senger, Gülsün Çavdar, Gürsel Ersan

Cover File

Oğuz Karabay, Davut Özdemir, Ertuğrul Güçlü, Mustafa Yıldırım, Nevin İnce, Abdulkadir Küçükbayrak, Türkan Toka Özer, Erkan YULA, Özcan DEVECİ, Alicem TEKİN, Süleyman DURMAZ, Mustafa GÜLENÇ, Keramettin YANIK

Pediatric Tularemia presenting with a neck mass

Serhan Küpeli, Recep Tekin

A review of clinically suspected sepsis and meningitis in infants under 90 days old in a tertiary care center in Saudi Arabia

Elham Essa Bukhari, Abdulkarim Abdullah Alrabiaah

A case of Tinea incognito diagnosed coincidentally

Dilek Şatana, Yıldız Yeğenoğlu, Meltem Uzun, Zayre Erturan, Nezahat Gürler, Güzin Özarmağan

Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole

Orçun Pehlivan, Şebnem Çalık, Bora Yüksel

Frequency of Rotavirus and Enteric Adenoviruses among children with acute gastroenteritis in a district hospital

Türkan Toka Özer, Erkan Yula, Özcan Deveci, Alicem Tekin, Süleyman Durmaz, Mustafa Gülenç, Keramettin Yanık