Papular-purpuric Gloves and Socks Syndrome in a 46-year-old Man with Mycoplasma pneumoniae Respiratory Disease
Mycoplasma pneumoniae is a cause of upper and lower respiratory disease,
predominantly in children and young. Dermatologic manifestations of the
infection occur in 1-5% of the cases, most commonly as Stevens–Johnson Syndrome
and Erythema Multiforme. We present a 46-year-old previously healthy man heavy
smoker, who was admitted due to fatigue, chest pain, cough, and fever that
appeared seven days earlier. He was diagnosed pleuro-pneumonia caused by Mycoplasma pneumoniae. Apart from
bicytopenia as toxic extrapulmonary manifestation of the infection, he
developed a relatively novel pruritic
dermatosis - papular-purpuric gloves and socks syndrome (PPGSS). Under antibiotic treatment, disease had
favorable outcome. In the cases of PPGSS without known etiologic agent, testing for Mycoplasma pneumoniae might be useful to
reveal etiology of the syndrome, especially in adult subjects. Some of the known constitutional symptoms of PPGSS
such as fever and fatigue, may also belong to the co-existing viral or
bacterial infection. J Microbiol Infect Dis 2018; 8(4):158-161
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- 1) Bagot M, Revuz J. Papular-purpuric "gloves and socks" syndrome: primary infection with parvovirus B19? J Am Acad Dermatol 1991; 25:341-342. 2) Adısen E, Önder M. Papular-purpuric gloves and sock syndrome Acral manifestations of viral infections. Clin Dermatol 2017; 35: 40-49. 3) Heckler GT, Dal Ri NMK, Almeida HL Jr. Case for diagnosis. Papular-purpuric gloves and socks syndrome. An Bras Dermatol 2012; 87:793-794. 4) Servey JT, Reamy BV, Hodge J. David. Clinical presentations of parvovirus B19 infection. Am Fam Physician 2007; 75:373-376. 5) Gutermuth J, Nadas K, Zirbs M. Papular-purpuric gloves and socks syndrome. Lancet 2011; 378:198. 6) Hsieh MY, Huang PH. The juvenile variant of papular-purpuric gloves and socks syndrome and its association with viral infections. Br J Dermatol 2004; 151(1):201-206. 7) Pemira SM, Tolan RW Jr. Mycoplasma pneumoniae infection presenting as bullous papular purpuric gloves and socks syndrome: novel association and review of the literature. Clin Pediatr (Phila) 2011; 50:1140-1143. 8) Cherry JD. Anemia and mucocutaneous lesions due to Mycoplasma pneumoniae infections. Clin Infect Dis 1993; 17 (Suppl 1):S47-51. 9) Yamazaki T, Kenri T. Epidemiology of Mycoplasma pneumoniae Infections in Japan and Therapeutic Strategies for Macrolide-Resistant M. pneumoniae. Front Microbiol 2016; 7:693. eCollection 2016. 10) Brown RJ, Nguipdop-Djomo P, Zhao H, Stanford E, Spiller OB, Chalker VJ. Mycoplasma pneumoniae Epidemiology in England and Wales: A National Perspective. Front Microbiol 2016; 7:157. eCollection 2016. 11) Reittner P, Müller NL, Heyneman L, et al. Mycoplasma pneumoniae Pneumonia: Radiographic and High-resolution CT Features in 28 Patients. AJR Am J Roentgenol 2000; 174:37-41. 12) Waites KB, Xiao L, Liu Y, Balish MF, Atkinson TP. Mycoplasma pneumoniae from the respiratory tract and beyond. Clin Microbiol Rev 2017; 30:747-809. 13) Narita M. Pathogenesis of extrapulmonary manifestations of Mycoplasma pneumoniae infection with special reference to pneumonia. J Infect Chemother 2010; 16:162-169. 14) Bar Meir E, Amital H, Levy Y, Kneller A, Bar-Dayan Y, Shoenfeld Y. Mycoplasma pneumoniae-induced thrombotic thrombocytopenic purpura. Acta Haematol 2000; 103:112-115. 15) Chuh A, Zavar V, Law M, Sciallis G. Gianotti-Crosti syndrome, pityriasis rosea, asymmetrical periflexural exanthem, unilateral mediothoracic exanthem, eruptive pseudoangiomatosis, and papular-purpuric gloves and socks syndrome: A brief review and arguments for diagnostic criteria. Infect Dis Rep 2012; 4: e12.
- ISSN: 2146-3158
- Başlangıç: 2011
- Yayıncı: Sağlık Araştırmaları Derneği