Tolga AYDOĞAN, Meltem HENDEK, Ebru OLGUN

Periodontal hastalık ve D vitamini ilişkisi

D vitamini, insan deri hücreleri tarafından sentezlenen veya diyet yoluyla tüketilen immünomodülatör, antienflamatuar, antiproliferatif etkilere sahip bir hormondur. D vitamini eksikliği kemik mineral yoğunluğunun azalmasına, osteoporoza, periodontal hastalıkların ilerlemesine ve çene kemiğinde rezorpsiyon oluşmasına neden olarak, periodontal hastalık riskini artırabilir. Ayrıca D vitamini kemik metabolizması, alveolar kemik rezorpsiyonu ve diş kayıplarının önlenmesi için de önemlidir. Diş eti epitel hücrelerinin antibakteriyel savunmasını arttırır ve dişeti enflamasyonunu azaltır, periodontal cerrahi sonrası postoperatif yara iyileşmesini hızlandırır ve periodontolojide profilaksi olarak kullanılan önemli bir takviyedir. Bu derlemenin amacı, periodontal hastalıkta D vitamininin rolünü vurgulamaktır.

Anahtar Kelimeler:

periodontitis, D vitamini, 25(OH)D3, Periodontal tedavi, 1.25(OH)2D3

Relationship between periodontal disease and vitamin D

Vitamin D is a hormone synthesized by human skin cells or consumed through diet with immunomodulatory, anti-inflammatory, and antiproliferative effects. Vitamin D deficiency may increase the risk of periodontal disease by causing decreased bone mineral density, osteoporosis, progression of periodontal diseases, and resorption of the jawbone. In addition, vitamin D is important for bone metabolism, alveolar bone resorption, and the prevention of tooth loss. It increases the antibacterial defense of gingival epithelial cells, reduces gingival inflammation, accelerates postoperative wound healing after periodontal surgery, and is a key supplement functioning as a prophylaxis in periodontology. The present review study aims to highlight the role of vitamin D in periodontal disease.

Keywords:

Periodontititis, vitamin D, 25(OH)D3, periodontal treatment, 1.25(OH)2D3,

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