Splenik Marjinal ZonLenfoma: Bir Olgu Sunumu

Marjinal zonlenfomalar(MZL) sekonderlenfoidfolliküllerinmarjinalzonunda bulunan B lenfositlerden köken alan düşük dereceli lenfomalardır. Dünya Sağlık Örgütü (WHO)'nün sınıfl andırmasına göre marjinalzonlenfomalar, ekstranodal MALT lenfoma, splenikMZL ve nodalMZL olmak üzere 3 alt gruba ayrılır. Her 3 grubun kromozomal, genetik ve immünfenotipik yönden benzerlikleri vardır. Ekstranodal MALT lenfomalar kemik iliği ve periferik lenf nodu tutuluşunun çok nadir görüldüğü, uzun süre lokalize bir kitle olarak kalan, mukoza ile ilişkili lenfoid dokuyu (MALT) tutan yavaş seyirli lenfomalardır. Biz burada halsizlik, yorgunluk şikayeti ile başvuran ve marjinalzonlenfoma tanısı konan 84 yaşındaki bayan olgu sunmayı amaçladık

Splenik Marjinal ZonLenfoma: Bir Olgu Sunumu

Marginal zone lymphomas (MZL) represent a group of low grade lymphomas whose cells originate from B lymphocytes normally present in marginal zone of the secondary lymphoid follicles. According to World Healt Organization (WHO) classifi cation, MZL is described with three subtypes: extranodal MALT lymphoma, splenic MZL and nodal MZL. All threemarginal zone cell lymphomass hareimmuno-phenotypic, genetic and chromosomal similarities. Extranodal MALT lymphoma is an indolent disease that presents within volvement of mucosa associated lenfoid tissue (MALT) by a long-persistent local-ized mass with less frequent bone marrow and peripheral lymphnode involvement. We would like to report a 84 year old woman with splenic marginal zone lymphoma who presented with weak ness and fatigue

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