Ramazan ASOĞLU, Emin ASOĞLU, Hakim ÇELİK, Serdar TÜRKMEN, Erdal AKTÜRK

ORTALAMA TROMBOSİT HACMİ/TROMBOSİT SAYISI (MPV/PLT) ORANI İLE KORONER YAVAŞ AKIM ARASINDAKİ İLİŞKİ

Amaç Koroner yavaş akim (KYA) koroner anatomik yapının normal olmasına rağmen anjiyografi sırasında verilen opak maddenin yavaşilerlediğinin gözlenmesi seklinde tanımlanmıştır. Akut koroner sendromlu hastalarda yapılan çalışmalarda olumsuz kardiyovasküler olaygelişimi ile trombosit arasında ilişki saptanmıştır. Bu çalışmada amacımız koroner yavaş� akımı varlığı ile ortalama trombosit hacmi/trombosit sayısı oranı arasındaki ilişkinin incelenmesidir.Metod veBulgularÇalışmamıza 200 hasta dahil edildi. Koroner yavaş akim grubunda MPV, MPV/PLT ve Trombosit değerlerinde KYA olmayan grubagöre anlamlı derecede fark izlendi (8.42±1.64, 7.77±1.51 p=0.04; 0.046±0.022, 0.03±0.01 p=0.01; 256.08±65.45, 236.38±59.28,p=0.02). Korelasyon analizinde KYA ile MPV, MPV/PLT ve Trombosit değerleri arasında pozitif yonde istatistiksel olarak anlamlı ilişkiizlendi (r=0.21 p=0.002; r=0.20, p=0.03; r=0.15, p=0.02)Sonuç Çalışmamızda MPV, trombosit ve MPV/PLT ile KYA arasında anlamlı ilişki bulundu. Bu trombosit parametrelerinin ölçümü ucuz ve yaygınolarak kullanılmaktadır ve KYA tanısında belirteç olarak kullanılması için prospektif çalışmalara ihtiyaç duyulmaktadır

Anahtar Kelimeler:

Koroner yavaş akim, trombosit, trombosit sayısı, ortalama trombosit hacmi

Relatıonshıp Between Coronary Slow Flow And Mean Platelet Volume/Platelet Count Ratıo

Aim Coronary Slow Flow (CSF) was defi ned with slow progression of the opaque substance against normal coronary anatomy duringangiography. Studies with acute coronary syndrome showed that there is a relationship between adverse cardiovascular events andplatelet. The goal of this study was to investigate the relationship between CSF and Mean Trombosit Volume/Trombosit count (MPV/PLT) ratio in patients with coronary slow fl ow.MaterialandMethod200 patients were included in our study. There was a signifi cant difference in MPV, MPV / PLT and Trombosit values in the CSF group according to non-CSF group (8.42±1.64, 7.77±1.51 p=0.04; 0.046±0.022, 0.03±0.01 p=0.01; 256.08±65.45, 236.38±59.28,p=0.02).There was a positive and signifi cant relationship between CSF and MPV, MPV / PLT ratio and platelet count in correlation analyze(r=0.21 p=0.002; r=0.20, p=0.03; r=0.15, p=0.02, respectively).Conclusion MPV, platelet count, and MPV / PLT ratio were signifi cantly related to CSF in our study.The measurement of these platelet parameters is cheap and widely used.In order to use as a marker of these parameters in the diagnosis of CSF, prospective studies are needed.

Keywords:

Coronary slow fl ow, Trombosit, Trombosit count, Mean Trombosit Volume,

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Başlangıç: 2015
Yayıncı: Ramazan AKDEMİR

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