Selçuk YAYLACI, Altuğ OSKEN, Ercan AYDIN, Ahmet Bilal GENÇ, Mustafa Volkan DEMİR, İbrahim KOCAYİĞİT, Salih ŞAHİNKUŞ, Yusuf CAN, Ceyhun VARIM

Deli Bal Zehirlenmeleri Genel Özellikler, Ulusal ve Uluslararası Literatürün İncelenmesi

Deli bal zehirlenmelerinde tipik zehirlenme tablosu; gastrointesti¬nal sistem irritasyonu, kardiyak aritmiler ve nörolojik belirtilerden oluşur. Ender olgu sunumlarında da deli bal ze-hirlenmesine bağlı hepatotoksisite, asistoli, miyokard enfarktüsü, elektrokardiyografik ST segment değişiklikleri, atriyal fibrilasyon, AV tam blok, senkop ve geçici iskemik atak benzeri tablo bildirilen vakalar mevcuttur. Toksik etkiler balın içerdiği grayanotok¬sinlerden kaynaklanır. Bu derlemede ülkemizde özellikle doğu karadeniz bölgesinde yoğun olarak karşılaşılan ve acil servislerde hayati tehtid eden deli bal zehirlenmelerinin genel özelliklerini literatür eşliğinde tartışmayı amaçladık.

Deli Bal Zehirlenmeleri Genel Özellikler, Ulusal ve Uluslararası Literatürün İncelenmesi

A typical course of poisoning consists of gastrointestinal system irritation, cardiac arrhythmias, and neurological symptoms. There are also reports of patients with hepatotoxicity, asystole, myocardial infarction, electrocardiographic ST-segment changes, atrial fibrillation, AV complete block, syncope and transient ischemic attack-like symptoms caused by mad honeypoisoning in rare case reports. The toxic effects are caused by the Grayanotoxin contained in the honey. In this review, we have tried to discuss the matter of mad honey poisoning, that is a serious threat in emergency services which occurs in east blacksea region.

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http://www.ncbi.nlm.nih.gov/pubmed (27.10.2015 tarihli taramada)
Hancı V, Bilir S, Kırtaç N, Akkız S, Yurtlu S, Turan IO. Mad Honey Poisoning
in Zonguldak Province: Analysis of 72 cases. J Turk Anaesth Int Care 2010;
(4):278-284.
Özhan H, Akdemir R, Yazici M, Gündüz H, Du¬ran S, Uyan C. Cardiac
emergencies caused by honey ingestion: a single centre experience. Emerg
Med J 2004;21:742-4.
Gündüz A, Turedi S, Uzun H, Topbas M. Mad ho¬ney poisoning. Am J
Emerg Med 2006;24:595-8.
Çetin NG, Marçıl E, Kıldıran M, Öğüt S. Hepatotoxicity with mad honey.
Turk J Emerg Med. 2009;9:84-6.
Gündüz A, Durmus I, Turedi S, Nuhoglu I, Oz¬turk S. Mad honey poisoningrelated
asystole. Emerg Med J 2007;24: 592-3.
Yarlioglues M, Akpek M, Ardic I, Elcik D, Sahin O, Kaya MG. Mad-honey
sexual activity and acute inferior myocardial infarctions in a married couple.
Tex Heart Inst J. 2011;38(5):577-80.
Yaylacı S, Osken A, Kocayigit I, Aydın E, Cakar MA, Tamer A, Gündüz
H. Electrocardiographic ST segment changes due to the mad honey
intoxication. Indian J Crit Care Med. 2013 May;17(3):192-3.
Osken A, Yaylacı S, Aydın E, Kocayigit I, Cakar MA, Tamer A, Gündüz H.
Slow ventricular response atrial fibrillation related to mad honey poisoning.
J Cardiovasc Dis Res. 2012 Jul;3(3):245-7.
Oguzturk H, Ciftci O, Turtay MG, Yumrutepe S. Complete atrioventricular
block caused by mad honey intoxication. Eur Rev Med Pharmacol Sci. 2012
Nov;16(12):1748-50.
Alp A, Sapnak S, Sezer SD, Colak C, Ozbakkaloglu M. A rare cause of
syncope among gerıatrıc patıents: mad honey ıntoxıcatıon. Turkish Journal
of Geriatrics 2012; 15 (1) 115-118.
Bilir O, Ersunan G, Yavasi O, Kayayurt K, Bayramoglu A. Mad honey
poısonıng presentıng as transıent ıschemıc attack. Turkish Journal of
Geriatrics 2014; 17 (2) 210-213
Gündüz A, Bostan H, Turedi S, Nuhoğlu I, Patan T. Wild flowers and mad
honey. Wilderness En¬viron Med 2007;18:69-71.
Aliyev F, Türkoğlu C, Çeliker C, Firatli İ, Alici G, Uzunhasan I. Chronic mad
honey intoxication syndrome: a new form of an old disease? Euro¬pace
;11:954-6.
Koca I, Koca AF. Poisoning by mad honey: A bri¬ef review. Food Chem
Toxicol 2007;45:1315-8.
Uzun H, Narci H, Tayfur I, Karabulut KU, Karcioglu O. Mad honey
intoxication: what is wrong with the blood glucose? a study on 46 patients.
Eur Rev Med Pharmacol Sci. 2013 Oct;17(20):2728-31.
Yaylaci S, Kocayigit I, Aydin E, Osken A, Genc AB, Cakar MA, Tamer A.
Clinical and laboratory findings in mad honey poisoning: a single center
experience. Niger J Clin Pract. 2014 Sep-Oct;17(5):589-93.
S. Yaylacı, O. Ayyıldız, E. AydIN, A. Osken, F. Karahalil, C. Varım, M.V. Demir,
A.B. Genç, S. Sahinkus, Y. Can, İ. Kocayigit, C. Bilir. Is there a difference in
mad honey poisoning between geriatric and non-geriatric patient groups?
Eur Rev Med Pharmacol Sci 2015:19 (23):4647-4653.
Demircan A, Keleş A, Bildik F, Aygencel G, Do¬ğan ON, Gómez HF. Mad
honey sex: therapeutic misadventures from an ancient biological wea¬pon.
Ann Emerg Med. 2009 Dec;54(6):824-9.
Oztasan N, Altınkaynak K, Akcay F, Gocer F, Dane S. Effects of made honey
on blood glucose and lipid levels in rats with Streptozocin-induced diabetes.
Turk J Vet Anim Sci 2005; 29: 1093-1096.20.
Gündüz A, Meriçé ES, Baydın A, et al. Does mad honey poisoning require
hospital admission? Am J Emerg Med 2009;27:424-7.
Cakar MA, Can Y, Vatan MB, Demirtas S, Gunduz H, Akdemir R. Atrial
fibrillation induced by mad honey intoxication in a patient with Wolf-
Parkinson-White syndrome. Clin Toxicol (Phila). 2011 Jun;49(5):438-9.
Yaylacı S, Osken A, Olt S, Temiz T, Tamer A.Gündüz H. Mad honey poisoning
accompanied by hypotension and bradycardia. Sakaryamj;2011(2):73-75.
Gündüz A, Tatlı Ö, Türedi S. Mad honey poisoning from the past to the
present. Turk J Emerg Med 2008;8:46-9.
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